Results 191 to 200 of about 104,935 (243)

Salivary biomarkers in sleep‐related disorders

Sleep Research, EarlyView.
Abstract The exploration of salivary biomarkers has emerged as a promising avenue in the diagnosis and management of sleep‐related disorders, such as obstructive sleep apnea (OSA), insomnia, and sleep deprivation. Saliva is a noninvasive biofluid that contains a wealth of biological markers, reflecting both local and systemic physiological changes ...
Chuan Xiang Li, Yi Wang, Ying Ni Lin, Jun Qi Lin, Ya Ru Yan, Xian wen Sun, Liu Zhang, Shi Qi Li, Ning Li, Qing Yun Li   +9 more
wiley   +1 more source

Innovative 3D‐bioprinted microfibers in calcium phosphate cement platform with Nell‐1 to activate nerve‐bone axis for synergistic bone, vasculature, and nanofibrous nerve regeneration

Smart Molecules, EarlyView.
A 3D‐bioprinted platform with stem cells activates “nerve‐bone” signaling by enabling the spatiotemporal delivery of Nell‐1. This activation enhances neurovascular and bone regeneration through the CYFIP1 cascade. In rat calvarial defects, the platform doubled bone regeneration and nerve repair and tripled vascular density, resulting in superior ...
Minjia Zhu, Xinyi Li, Jingyi Li, Kan Yu, Zixiang Dai, Le Xiao, Qinrou Zhang, Zihan Jia, Qingchen Qiao, Zeqing Zhao, Ke Zhang, Yuxing Bai   +11 more
wiley   +1 more source

Media‐Dependent Growth, Stress Responses, and Metal Accumulation Patterns in Azolla imbricata (Roxb.) Nakai Exposed to As, Cd, Cu, Pb, and Zn: Individual and Combination Effects (Synergistic, Antagonistic, and Additive)

Environmental Toxicology, EarlyView.
ABSTRACT In this study, we examined metal accumulation and biochemical responses of Azolla imbricata (Roxb.) Nakai exposed to water medium (WM) and nutrient medium (NM) under single and combined (co‐exposure) treatments with five metals (As, Cd, Cu, Pb, and Zn) at 10% environmentally relevant concentrations.
Sung‐Chul Hong, Je‐Sung Park, Seong‐Ho Jang, Eun‐Sang Jung, Byung‐Gil Jung, Anisa Dea Novianti, Velmurugan Palanivel, Young‐Chae Song, Arpita Kumari, Geetha Parameswaran, Sivakumar Subpiramaniyam   +10 more
wiley   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

Environmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho, Chun‐Wei Tung, B. Linju Yen, Chen‐Yi Weng, Ju‐Hsin Hsu, Ming‐Hsien Tsai, Salim Arrokhman, Pinpin Lin   +7 more
wiley   +1 more source

Exposure to Structurally Related Organophosphate Esters Elicits Distinct Metabolomic Perturbations in Daphnia magna

Environmental Toxicology, EarlyView.
ABSTRACT Organophosphate esters (OPEs) are found ubiquitously in the environment and exposure to these chemicals has induced behavioral, developmental, and morphological impairments in several model organisms. Yet there is still a lack of understanding of how sub‐lethal exposure disrupts organism function at the molecular‐level, especially for Daphnia ...
Salwa Hajir, Sanam Yousifie, Karl J. Jobst, André J. Simpson, Myrna J. Simpson   +4 more
wiley   +1 more source

Multi‐gradient warming reshapes functional traits and adaptive responses of alpine meadow plants

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Plant functional traits in alpine meadows are critical indicators of ecosystem responses to climate warming, yet dynamic changes in trait networks across warming gradients and their consequences for community functions remain poorly understood.
Zhiwei Yan, Feipeng Ren, Haocun Zhao, Baoyang Sun, Hao Li, Jinquan Huang, Jigen Liu   +6 more
wiley   +1 more source

[Some problems of proline metabolism].

Postepy biochemii, 1968
openaire   +1 more source

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Proline metabolism as regulatory hub

Trends in Plant Science, 2022
Proline is a multifunctional amino acid that is accumulated in high concentrations in plants under various stress conditions. Proline accumulation is intimately connected to many cellular processes, such as osmotic pressure, energy status, nutrient availability, changes in redox balance, and defenses against pathogens.
Maria Elena Alvarez, Arnould Savouré, László Szabados   +2 more
exaly   +4 more sources

Proline metabolism in cancer

Amino Acids, 2021
Cancer cells often change their metabolism to support uncontrolled proliferation. Proline is the only proteogenic secondary amino acid that is abundant in the body. Recent studies have shown that proline metabolism plays an important role in metabolic reprogramming and affects the occurrence and development of cancer.
Guowang Xu, Wangshu Qin, Xu Guowang
exaly   +3 more sources