Prolonged QT Interval in Cirrhosis: Twisting Time? [PDF]
Gut and Liver, 2022 Approximately 30% to 70% of patients with cirrhosis have QT interval prolongation. In patients without cirrhosis, QT prolongation is associated with an increased risk of ventricular arrhythmias, such as torsade de pointes (TdP).
William Lee +3 more
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Prolonged QT Interval in a Patient With Coronavirus Disease-2019: Beyond Hydroxychloroquine and Azithromycin [PDF]
Journal of Investigative Medicine High Impact Case Reports, 2020 Recent reports have suggested an increased risk of QT prolongation and subsequent life-threatening ventricular arrhythmias, particularly torsade de pointes, in patients with coronavirus disease-2019 (COVID-19) treated with hydroxychloroquine and ...
B K Anupama MBBS +2 more
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Prolonged QT Interval in SARS-CoV-2 Infection: Prevalence and Prognosis. [PDF]
J Clin Med, 2020 [EN] Background: The prognostic value of a prolonged QT interval in SARS-Cov2 infection is not well known. Objective: To determine whether the presence of a prolonged QT on admission is an independent factor for mortality in SARS-Cov2 hospitalized ...
Farré N +12 more
europepmc +4 more sources
Incident prolonged QT interval in midlife and late-life cognitive performance. [PDF]
PLoS ONE, 2020 BackgroundMeasures of cardiac ventricular electrophysiology have been associated with cognitive performance in cross-sectional studies. We sought to evaluate the association of worsening ventricular repolarization in midlife, as measured by incident ...
Claudia K Suemoto +9 more
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Metformin Shortens Prolonged QT Interval in Diabetic Mice by Inhibiting L-Type Calcium Current: A Possible Therapeutic Approach [PDF]
Frontiers in Pharmacology, 2020 The incidence and mortality of cardiovascular disease in diabetic patients are 2-3 times higher than those in non-diabetic patients. Abnormal function of the L-type calcium channel in myocardial tissue might result in multiple cardiac disorders such as a
Hui Wang +9 more
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Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging. [PDF]
Theranostics, 2022 Rationale: Aging in the heart is a gradual process, involving continuous changes in cardiovascular cells, including cardiomyocytes (CMs), namely cellular senescence.
Lazzarini E +14 more
europepmc +4 more sources
Increased prevalence of prolonged QT interval in males with primary or secondary hypogonadism: A pilot study [PDF]
International Journal of Andrology, 2009 P>Symptoms and signs of male hypogonadism span all organ systems, including the cardiovascular apparatus. The electrocardiographic QT interval reflects cardiac ventricular repolarization and, if prolonged, increases the risk of malignant arrhythmias ...
F. Pecori Giraldi +6 more
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Screening for QT Prolongation in the Emergency Department: Is There a Better “Rule of Thumb?” [PDF]
Western Journal of Emergency Medicine, 2020 Introduction: Identification of QT prolongation in the emergency department (ED) is critical for appropriate monitoring, disposition, and treatment of patients at risk for torsades de pointes (TdP).
Megan L. Rischall +2 more
doaj +3 more sources
Epidemiology and related risk factors of prolonged QT interval in neonates. [PDF]
Pak J Med SciHong Y, Wang Y, Zhou Q, Wang M, Zhou J.
europepmc +3 more sources
Prolongation of the QT interval under treatment with hydroxychloroquine in a patient with systemic lupus erythematosus: A case report [PDF]
Romanian Journal of Rheumatology, 2022 Hydroxychloroquine (HCQ) is an antimalarial used in the treatment of patients with systemic lupus erythematosus (SLE). HCQ has a good safety profile and favorable results in terms of controlling clinical manifestations in SLE.
Ioan-Teodor Dragoi +4 more
doaj +1 more source