Results 11 to 20 of about 708 (69)

Acquired long QT syndrome in chronic kidney disease patients

Renal Failure, 2020
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in chronic kidney disease (CKD) patients. QT interval prolongation is a congenital or acquired condition that is associated with an increased risk of torsade de pointes (TdP ...
Peng Liu, Lu Wang, Dan Han, Chaofeng Sun, Xiaolin Xue, Guoliang Li   +5 more
doaj   +1 more source

QT is longer in drug-free patients with schizophrenia compared with age-matched healthy subjects. [PDF]

PLoS ONE, 2014
The potassium voltage-gated channel KCNH2 is a well-known gene in which mutations induce familial QT interval prolongation. KCNH2 is suggested to be a risk gene for schizophrenia.
Kumiko Fujii, Yuji Ozeki, Hiroaki Okayasu, Yumiko Takano, Takahiro Shinozaki, Hiroaki Hori, Masami Orui, Minoru Horie, Hiroshi Kunugi, Kazutaka Shimoda   +9 more
doaj   +1 more source

Long QT syndrome and torsades de pointes complicating mitral valve replacement

Indian Heart Journal, 2016
Severe QT interval prolongation >500 ms occurs in one quarter of cardiac surgical patients in the perioperative period while moderate prolongation occurs in most of them. Prolonged QT interval may be associated with torsades de pointes and lead to sudden
Shegu Gilbert, Devender Singh, M. Lawrance Jesuraj   +2 more
doaj   +1 more source

QT PRODACT: In Vivo QT Assay With a Conscious Monkey for Assessment of the Potential for Drug-Induced QT Interval Prolongation

Journal of Pharmacological Sciences, 2005
In safety pharmacology studies, the effects on the QT interval of electrocardiograms are routinely assessed using a telemetry system in cynomolgus monkeys. However, there is a lack of integrated databases concerning in vivo QT assays in conscious monkeys.
Kentaro Ando, Toshiyasu Hombo, Akihiro Kanno, Hironobu Ikeda, Masakazu Imaizumi, Noritsugu Shimizu, Kengo Sakamoto, Shin-ichi Kitani, Yoshinori Yamamoto, Shingo Hizume, Keiko Nakai, Tetsuya Kitayama, Keiji Yamamoto   +12 more
doaj   +1 more source

Metformin Shortens Prolonged QT Interval in Diabetic Mice by Inhibiting L-Type Calcium Current: A Possible Therapeutic Approach

Frontiers in Pharmacology, 2020
The incidence and mortality of cardiovascular disease in diabetic patients are 2-3 times higher than those in non-diabetic patients. Abnormal function of the L-type calcium channel in myocardial tissue might result in multiple cardiac disorders such as a
Hui Wang, Cao Wang, Yuan Lu, Yan Yan, Dongjing Leng, Shanshan Tian, Dongjie Zheng, Zhiguo Wang, Yunlong Bai, Yunlong Bai   +9 more
doaj   +1 more source

Prolonged QT interval in the infants of diabetic mothers [PDF]

Journal of Kerman University of Medical Sciences, 2019
Background: The prevalence of gestational diabetes mellitus is rising. Myocardial hypertrophy is the most common cardiac disorder in the infants of diabetic mothers, which hypothetically can cause fatal arrhythmias.
Mohammad Mehdi Bagheri, Ahmad Naghibzadeh-Tahami, Pedram Niknafs, Zahra Daei   +3 more
doaj   +1 more source

Corrected QT interval and QT dispersion in temporal lobe epilepsy

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021
Background Cardiac arrhythmias are expected among patients with epilepsy due to the effect of anti-epileptic drugs. Temporal lobe epilepsy also causes autonomic seizures that may affect heart rhythm.
Maram Samy Nasef, Ahmed Abdelmonem Gaber, Yousry Aboelnaga Abdelhamid, Islam Bastawy, Salem Taha Abdelhady, Mona Mokhtar Wahid el din   +5 more
doaj   +1 more source

Prevalence of Long QT Syndrome in Children with Congenital Sensory-Neural Deafness

Journal of Ardabil University of Medical Sciences, 2021
Background & objectives: Long QT syndrome (LQTS), congenital or acquired disorder, is characterized by a prolonged QT interval associated with syncope attacks and sudden death.
Ahmad Jamei Khosroshahi, Mahmoud Samadi, Shamsi Ghaffari, Akbar Molaei, Fatemeh Chakari   +4 more
doaj  

Prevalence of QT interval prolongation in inflammatory bowel disease

The Turkish Journal of Gastroenterology, 2016
Background/Aims: There is growing evidence linking various cardiac complications with inflammatory bowel disease (IBD). Electrolyte abnormalities, chronic inflammation, and medication use (such as Infliximab) that are associated with IBD are all ...
Deepak J. Pattanshetty, Rama Dilip Gajulapalli, Kiran Anna, Raja Shekhar Sappati Biyyani   +3 more
doaj   +1 more source

QTc interval on 24‐hour holter monitor: To trust or not to trust?

Annals of Noninvasive Electrocardiology, 2022
Introduction QT interval represents the ventricular depolarization and repolarization. Its accurate measurement is critical since prolonged QT can lead to sudden cardiac death.
Mhd Khalil Tamr Agha, Ghina Fakhri, Mohamed Ahmed, Omar El Sedawy, Bernard Abi Saleh, Fadi Bitar, Mariam Arabi   +6 more
doaj   +1 more source