Prolonged QT Interval: A Tricky Diagnosis? [PDF]
Prolonged heart-rate adjusted QT intervals on the electrocardiogram (ECG) are associated with an increased risk for coronary heart disease and sudden death. However, the diagnosis of the prolonged QT interval is hampered by lack of standards. We studied variations in the prevalence of prolonged QT, based on different common definitions, in a large ...
M C, de Bruyne +6 more
openaire +4 more sources
In safety pharmacology studies, the effects on the QT interval of electrocardiograms are routinely assessed using a telemetry system in cynomolgus monkeys. However, there is a lack of integrated databases concerning in vivo QT assays in conscious monkeys.
Kentaro Ando +12 more
doaj +2 more sources
QT interval prolongation after Premature Ventricular Contractions (PVCs) [PDF]
Long QT syndrome (LQTS) is an inherited ion channelopathy resulting in abnormal ventricular repolarization and abnormal prolongation of QT interval on the ECG. Syncope, fainting, cardiac arrest, and sudden death are common manifestations of LQTS.
Mohammed Haroon Rashid +4 more
doaj +1 more source
Prolonged Tp-e Interval, Tp-e/QT Ratio and Tp-e/QTc Ratio in Patients with Type 2 Diabetes Mellitus [PDF]
BackgroundType 2 diabetes mellitus (T2DM) is associated with increased risk of malignant ventricular arrhythmias. Cardiac electrical inhomogeneity may be the leading cause of the increased arrhythmic risk in patients with T2DM.
Alptug Tokatli +4 more
doaj +3 more sources
Long QT interval in resting electrocardiogram – and what next? Sports cardiologist’s pointofview. Part 1. From electrophysiology to diagnostics [PDF]
Electrocardiography is the most common and available cardiovascular diagnostic procedure and an important tool in everyday clinical practice of a family physician. Electrocardiogram interpretation is therefore an invaluable clinical skill.
Zbigniew Krenc
doaj +2 more sources
Prolongation of the QT interval by ketanserin [PDF]
Summary In hypertensive patients single doses of ketanserin 40 mg prolonged the corrected QT interval (QTc) for at least 8 hours, with a maximal increase of 35 ms (P less than 0.001, n = 6) after 2 hours. During chronic dosing (20 and 40 mg b.d.) the QTc was further prolonged, by 46 and 45 ms respectively.
H A, Cameron, P C, Waller, L E, Ramsay
openaire +2 more sources
[QT Interval and Its Prolongation - What Does It Mean?] [PDF]
The assessment of the QT interval has been an integral part of ECG interpretation since the first descriptions of long QT syndrome by Wolff in 1950 and by Jervell and Lange-Nielsen in 1957.
Castiglione, Alessandro, Odening, Katja
core +1 more source
Clinical-pharmacological aspects of the safe use of medicines, causing prolongation of QT interval
Specific aspects of manifestation of prolonged QT syndrome, developed during the use of drugs belonging to different pharmacological groups are discussed. It analyses data on dangerous combinations of drugs that prolong the QT interval.
O. A. Demidova +3 more
doaj +1 more source
Prolonged QT Interval in SARS-CoV-2 Infection: Prevalence and Prognosis [PDF]
[EN] Background: The prognostic value of a prolonged QT interval in SARS-Cov2 infection is not well known. Objective: To determine whether the presence of a prolonged QT on admission is an independent factor for mortality in SARS-Cov2 hospitalized ...
García-Durán, Ana B. +12 more
core +3 more sources
Novel genes for QTc interval. How much heritability is explained, and how much is left to find? [PDF]
The corrected QT (QTc) interval is a complex quantitative trait, believed to be influenced by several genetic and environmental factors. It is a strong prognostic indicator of cardiovascular mortality in patients with and without cardiac disease.
Spector, Timothy D. +9 more
core +1 more source

