Results 1 to 10 of about 53,127 (203)

Prolonged QT Interval in Cirrhosis: Twisting Time? [PDF]

Gut and Liver, 2022
Approximately 30% to 70% of patients with cirrhosis have QT interval prolongation. In patients without cirrhosis, QT prolongation is associated with an increased risk of ventricular arrhythmias, such as torsade de pointes (TdP).
William Lee, Bert Vandenberk, Satish R. Raj, Samuel S. Lee   +3 more
doaj   +2 more sources

Incident prolonged QT interval in midlife and late-life cognitive performance. [PDF]

PLoS ONE, 2020
BackgroundMeasures of cardiac ventricular electrophysiology have been associated with cognitive performance in cross-sectional studies. We sought to evaluate the association of worsening ventricular repolarization in midlife, as measured by incident ...
Claudia K Suemoto, Laura E Gibbons, Evan L Thacker, Jonathan D Jackson, Claudia L Satizabal, Brianne M Bettcher, Lenore Launer, Caroline Phillips, Lon R White, Melinda C Power   +9 more
doaj   +2 more sources

Prolonged QT Interval in a Patient With Coronavirus Disease-2019: Beyond Hydroxychloroquine and Azithromycin [PDF]

Journal of Investigative Medicine High Impact Case Reports, 2020
Recent reports have suggested an increased risk of QT prolongation and subsequent life-threatening ventricular arrhythmias, particularly torsade de pointes, in patients with coronavirus disease-2019 (COVID-19) treated with hydroxychloroquine and ...
B K Anupama MBBS, Soumya Adhikari MBBS, Debanik Chaudhuri MD   +2 more
doaj   +2 more sources

Screening for QT Prolongation in the Emergency Department: Is There a Better “Rule of Thumb?” [PDF]

Western Journal of Emergency Medicine, 2020
Introduction: Identification of QT prolongation in the emergency department (ED) is critical for appropriate monitoring, disposition, and treatment of patients at risk for torsades de pointes (TdP).
Megan L. Rischall, Stephen W. Smith, Ari B. Friedman   +2 more
doaj   +3 more sources

Beyond a prolonged QT interval. [PDF]

JRSM Short Rep, 2013
A hypocalcaemia case is presented with convulsions, electrocardiogram (ECG) changes and laboratory findings suggestive of osteomalacia. This case constitutes a rare presentation of osteomalacia-induced hypocalcaemia.
Bitar ZI, Maadarani O, Alfayed H, Bitar M.   +3 more
europepmc   +3 more sources

Metformin Shortens Prolonged QT Interval in Diabetic Mice by Inhibiting L-Type Calcium Current: A Possible Therapeutic Approach [PDF]

Frontiers in Pharmacology, 2020
The incidence and mortality of cardiovascular disease in diabetic patients are 2-3 times higher than those in non-diabetic patients. Abnormal function of the L-type calcium channel in myocardial tissue might result in multiple cardiac disorders such as a
Hui Wang, Cao Wang, Yuan Lu, Yan Yan, Dongjing Leng, Shanshan Tian, Dongjie Zheng, Zhiguo Wang, Yunlong Bai, Yunlong Bai   +9 more
doaj   +2 more sources

Prolongation of the QT interval under treatment with hydroxychloroquine in a patient with systemic lupus erythematosus: A case report [PDF]

Romanian Journal of Rheumatology, 2022
Hydroxychloroquine (HCQ) is an antimalarial used in the treatment of patients with systemic lupus erythematosus (SLE). HCQ has a good safety profile and favorable results in terms of controlling clinical manifestations in SLE.
Ioan-Teodor Dragoi, Alexandra Maria Burlui, Luana Macovei, Patricia Richter, Elena Rezus   +4 more
doaj   +1 more source

Estimation of cardiac QTc intervals in people prescribed antipsychotics: a comparison of correction factors

Therapeutic Advances in Psychopharmacology, 2022
Background: A prolonged electrocardiogram (ECG) QT interval is associated with cardiac events and increased mortality. Antipsychotics can prolong the QT interval.
Teodora Andric, Karl Winckel, Timothy David Tanzer, Samantha Hollingworth, Lesley Smith, Katherine Isoardi, Olivier Tan, Dan Siskind   +7 more
doaj   +1 more source

Prevalence of QTc interval prolongation and its associated risk factors among psychiatric patients: a prospective observational study

BMC Psychiatry, 2020
Background QT interval prolongation is a growing concern worldwide, posing psychiatric patients to life-threatening fatal arrhythmias i.e., torsade de pointes.
Zahid Ali, Mohammad Ismail, Zahid Nazar, Fahadullah Khan, Qasim Khan, Sidra Noor   +5 more
doaj   +1 more source

Prolongation of the QT interval by ketanserin [PDF]

Postgraduate Medical Journal, 1988
Summary In hypertensive patients single doses of ketanserin 40 mg prolonged the corrected QT interval (QTc) for at least 8 hours, with a maximal increase of 35 ms (P less than 0.001, n = 6) after 2 hours. During chronic dosing (20 and 40 mg b.d.) the QTc was further prolonged, by 46 and 45 ms respectively.
H A, Cameron, P C, Waller, L E, Ramsay
openaire   +2 more sources