Results 21 to 30 of about 1,444,780 (246)

Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta-Analysis of Three Genome-Wide Association Studies [PDF]

open access: yes, 2009
To identify loci affecting the electrocardiographic QT interval, a measure of cardiac repolarisation associated with risk of ventricular arrhythmias and sudden cardiac death, we conducted a meta-analysis of three genome-wide association studies (GWAS ...
Rice, K. (Kenneth)   +285 more
core   +1 more source

Beyond a prolonged QT interval

open access: yesJRSM Short Reports, 2013
A hypocalcaemia case is presented with convulsions, electrocardiogram (ECG) changes and laboratory findings suggestive of osteomalacia. This case constitutes a rare presentation of osteomalacia-induced hypocalcaemia.
Bitar, Zouheir Ibrahim   +3 more
openaire   +2 more sources

Prolonged QT interval in Rett syndrome [PDF]

open access: yesArchives of Disease in Childhood, 1999
Rett syndrome is a severe neurodevelopmental disorder of unknown aetiology. A prolonged QT interval has been described previously in patients with Rett syndrome. To investigate QT prolongation and the presence of cardiac tachyarrhythmias in Rett syndrome electrocardiography and 24 hour Holter monitoring were performed prospectively in a cohort of 34 ...
C J, Ellaway   +3 more
openaire   +2 more sources

Acquired long QT syndrome in chronic kidney disease patients

open access: yesRenal Failure, 2020
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in chronic kidney disease (CKD) patients. QT interval prolongation is a congenital or acquired condition that is associated with an increased risk of torsade de pointes (TdP ...
Peng Liu   +5 more
doaj   +1 more source

QT is longer in drug-free patients with schizophrenia compared with age-matched healthy subjects. [PDF]

open access: yesPLoS ONE, 2014
The potassium voltage-gated channel KCNH2 is a well-known gene in which mutations induce familial QT interval prolongation. KCNH2 is suggested to be a risk gene for schizophrenia.
Kumiko Fujii   +9 more
doaj   +1 more source

Prolonged QT interval in bulimia nervosa [PDF]

open access: yesBMJ Case Reports, 2011
A 39-year-old woman with an unremarkable history presented to the emergency department with three episodes of collapse. Each episode was witnessed by her son who described a loss of consciousness followed by rapid and complete recovery. The patient appeared well and examination was unremarkable.
Ryan, Buchanan   +2 more
openaire   +2 more sources

Long QT syndrome and torsades de pointes complicating mitral valve replacement

open access: yesIndian Heart Journal, 2016
Severe QT interval prolongation >500 ms occurs in one quarter of cardiac surgical patients in the perioperative period while moderate prolongation occurs in most of them. Prolonged QT interval may be associated with torsades de pointes and lead to sudden
Shegu Gilbert   +2 more
doaj   +1 more source

Increased prevalence of prolonged QT interval in males with primary or secondary hypogonadism : a pilot study [PDF]

open access: yes, 2009
P>Symptoms and signs of male hypogonadism span all organ systems, including the cardiovascular apparatus. The electrocardiographic QT interval reflects cardiac ventricular repolarization and, if prolonged, increases the risk of malignant arrhythmias ...
P. M. Toja   +6 more
core   +1 more source

Metformin Shortens Prolonged QT Interval in Diabetic Mice by Inhibiting L-Type Calcium Current: A Possible Therapeutic Approach

open access: yesFrontiers in Pharmacology, 2020
The incidence and mortality of cardiovascular disease in diabetic patients are 2-3 times higher than those in non-diabetic patients. Abnormal function of the L-type calcium channel in myocardial tissue might result in multiple cardiac disorders such as a
Hui Wang   +9 more
doaj   +1 more source

Prolonged QT interval in the infants of diabetic mothers [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2019
Background: The prevalence of gestational diabetes mellitus is rising. Myocardial hypertrophy is the most common cardiac disorder in the infants of diabetic mothers, which hypothetically can cause fatal arrhythmias.
Mohammad Mehdi Bagheri   +3 more
doaj   +1 more source

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