Results 21 to 30 of about 708 (69)

Sensitivity of inhalation anesthetics isoflurane and sevoflurane for the drug-induced QT-interval prolongation in guinea pigs

Journal of Pharmacological Sciences, 2020
We investigated effects of isoflurane and sevoflurane on sparfloxacin-induced QT-interval prolongation in guinea pigs under the monitoring of electrocardiogram and monophasic action potential (MAP), which was compared with those of halothane or non ...
Yoshinobu Nagasawa, Kaori Sakai, Rui Kurimoto, Satoshi Kawakami, Megumi Aimoto, Akira Takahara   +5 more
doaj   +1 more source

Effect of Hydroxychloroquine and Azithromycin on QT Interval Prolongation and Other Cardiac Arrhythmias in COVID-19 Confirmed Patients

Cardiovascular Therapeutics, 2021
Background. Hydroxychloroquine with or without azithromycin was one of the common therapies at the beginning of the COVID-19 pandemic. They can prolong QT interval, cause torsade de pointes, and lead to sudden cardiac death.
Seyed Parsa Eftekhar, Sohrab Kazemi, Mohammad Barary, Mostafa Javanian, Soheil Ebrahimpour, Naghmeh Ziaei   +5 more
doaj   +1 more source

Epicardial adipose tissue predicted prolonged QTc interval in patients with arterial hypertension

Clinical and Experimental Hypertension, 2021
Introduction: It is important to identify those at higher risk for ventricular arrhythmia among hypertensive patients. Epicardial adipose tissue (EAT) leads to electromechanical changes in the heart by endocrine and paracrine effects with cytokines and ...
Ahmet Seyda Yılmaz, Göksel Çinier, Ömer Faruk Çırakoğlu, Mustafa Çetin   +3 more
doaj   +1 more source

Drug-Induced QT Prolongation as a Result of an Escitalopram Overdose in a Patient with Previously Undiagnosed Congenital Long QT Syndrome

Case Reports in Medicine, 2014
We present a case of drug-induced QT prolongation caused by an escitalopram overdose in a patient with previously undiagnosed congenital LQTS. A 15-year-old Caucasian female presented following a suicide attempt via an escitalopram overdose.
Paul Singh, J. Martin Maldonado-Duran
doaj   +1 more source

QT interval prolongation after Premature Ventricular Contractions (PVCs) [PDF]

Electronic Physician, 2010
Long QT syndrome (LQTS) is an inherited ion channelopathy resulting in abnormal ventricular repolarization and abnormal prolongation of QT interval on the ECG. Syncope, fainting, cardiac arrest, and sudden death are common manifestations of LQTS.
Mohammed Haroon Rashid, Kakhaber Etsadashvilli, Anzor Melia, Khatuna Jalabadze, Ia Avaliani   +4 more
doaj  

Torsade de Pointes Triggered by Early Ventricular Escape Beats in a Patient with Complete Atrioventricular Block

Case Reports in Cardiology, 2016
Torsade de pointes is an uncommon and malignant form of polymorphic ventricular tachycardia and associated with a prolonged QT interval, which may be congenital or acquired.
Erkan Yildirim, Baris Bugan, Suat Gormel, Uygar Cagdas Yuksel, Murat Celik, Yalcin Gokoglan, Serdar Firtina, Sinan Iscen, Emre Yalcinkaya, Ugur Kucuk, Hasan Kutsi Kabul   +10 more
doaj   +1 more source

Prolonged Tp-e Interval, Tp-e/QT Ratio and Tp-e/QTc Ratio in Patients with Type 2 Diabetes Mellitus [PDF]

Endocrinology and Metabolism, 2016
BackgroundType 2 diabetes mellitus (T2DM) is associated with increased risk of malignant ventricular arrhythmias. Cardiac electrical inhomogeneity may be the leading cause of the increased arrhythmic risk in patients with T2DM.
Alptug Tokatli, Fethi Kiliçaslan, Metin Alis, Omer Yiginer, Mehmet Uzun   +4 more
doaj   +1 more source

Effects of the Antitussive Drug Cloperastine on Ventricular Repolarization in Halothane-Anesthetized Guinea Pigs

Journal of Pharmacological Sciences, 2012
Cloperastine is an antitussive drug, which can be received as an over-the-counter cold medicine. The chemical structure of cloperastine is quite similar to that of the antihistamine drug diphenhydramine, which is reported to inhibit hERG K+ channels and ...
Akira Takahara, Kaori Fujiwara, Atsushi Ohtsuki, Takayuki Oka, Iyuki Namekata, Hikaru Tanaka   +5 more
doaj   +1 more source

Suppression of amiodarone‐induced torsade de pointes by landiolol in a patient with atrial fibrillation‐mediated cardiomyopathy

Annals of Noninvasive Electrocardiology, 2021
An elderly Japanese woman developed acute decompensated heart failure caused by persistent atrial fibrillation (AF) and left ventricular systolic dysfunction.
Koji Takahashi, Mina Yamashita, Tomoki Sakaue, Daijiro Enomoto, Shigeki Uemura, Takafumi Okura, Shuntaro Ikeda, Masafumi Takemoto, Yutaka Utsunomiya, Takashi Hyodo   +9 more
doaj   +1 more source

Torsade de pointes in liver transplantation recipient after induction of general anesthesia: a case report [PDF]

Korean Journal of Anesthesiology, 2014
Torsade de pointes (TdP) is an uncommon and specific form of polymorphic ventricular tachycardia, associated with a prolonged QT interval. Prolongation of the QT interval is the most widely recognized electrophysiological abnormality in patients with ...
Eun-Jin Chung, Yun-Seok Jeon, Hyun-Joo Kim, Kook Hyun Lee, Ji-Won Lee, Kyoung-Ah Han, Seung-Hwan Jung   +6 more
doaj   +1 more source