Results 31 to 40 of about 113,542 (365)
QT peak prolongation predicts cardiac death following stroke [PDF]
, 2015 Cardiac death has been linked in many populations to prolongation of the QT interval (QTe). However, basic science research suggested that the best estimate of the time point when repolarisation begins is near the T-wave peak.
Douglas, Denise +7 more
core +1 more source
Pharmacogenetics of Drug-Induced QT Interval Prolongation: An Update [PDF]
, 2015 A prolonged QT interval is an important risk factor for ventricular arrhythmias and sudden cardiac death. QT prolongation can be caused by drugs. There are multiple risk factors for drug-induced QT prolongation, including genetic variation.
Berg, M.E. (Marten) van den +4 more
core +1 more source
Trigger versus Substrate: Multi-Dimensional Modulation of QT-Prolongation Associated Arrhythmic Dynamics by a hERG Channel Activator [PDF]
, 2017 Background: Prolongation of the QT interval of the electrocardiogram (ECG), underlain by prolongation of the action potential duration (APD) at the cellular level, is linked to increased vulnerability to cardiac arrhythmia.
Antzelevitch +57 more
core +2 more sources
Prolonged QT interval in bulimia nervosa [PDF]
BMJ Case Reports, 2011 A 39-year-old woman with an unremarkable history presented to the emergency department with three episodes of collapse. Each episode was witnessed by her son who described a loss of consciousness followed by rapid and complete recovery. The patient appeared well and examination was unremarkable.
Ryan, Buchanan +2 more
openaire +2 more sources
Hepatology, EarlyView., 2022 Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou +13 more
wiley +1 more source
AIDS (London), 2019 : Abnormal electrocardiograms (ECG) are associated with increased risk of arrhythmias and sudden cardiac death. We aimed to investigate the prevalence and associated risk factors of prolonged QTc and major ECG abnormalities, in persons living with HIV ...
A. Knudsen +13 more
semanticscholar +1 more source
Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
Journal of Pharmacological Sciences, 2005 The purpose of this study was to assess the utility of the isoflurane-anesthetized dog model for detecting the potential for QT interval prolongation by human pharmaceuticals.
Hiroyuki Tashibu +4 more
doaj +1 more source
Acquired long QT syndrome in chronic kidney disease patients
Renal Failure, 2020 Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in chronic kidney disease (CKD) patients. QT interval prolongation is a congenital or acquired condition that is associated with an increased risk of torsade de pointes (TdP ...
Peng Liu +5 more
doaj +1 more source
QT is longer in drug-free patients with schizophrenia compared with age-matched healthy subjects. [PDF]
PLoS ONE, 2014 The potassium voltage-gated channel KCNH2 is a well-known gene in which mutations induce familial QT interval prolongation. KCNH2 is suggested to be a risk gene for schizophrenia.
Kumiko Fujii +9 more
doaj +1 more source