Results 71 to 80 of about 28,299 (224)

Structural and biochemical insights of CypA and AIF interaction [PDF]

, 2017
The Cyclophilin A (CypA)/Apoptosis Inducing Factor (AIF) complex is implicated in the DNA degradation in response to various cellular stress conditions, such as oxidative stress, cerebral hypoxia-ischemia and traumatic brain injury.
Caporale, Andrea, Chambery, Angela, Di Sorbo, Gianluigi, Doti, Nunzianna, Farina, Biancamaria, Fattorusso, Roberto, Leoni, Guido, Mascanzoni, Fabiola, Raimondo, Domenico, Russo, Rosita, Ruvo, Menotti   +10 more
core   +1 more source

Pin1 Prolyl Isomerase Regulates Endothelial Nitric Oxide Synthase [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2011
Objective— The Pin1 prolyl isomerase acts in concert with proline-directed protein kinases to regulate function of protein substrates through isomerization of peptide bonds that link phosphoserine or phosphothreonine to proline.
Ling, Ruan, Christina M, Torres, Jin, Qian, Feng, Chen, James D, Mintz, David W, Stepp, David, Fulton, Richard C, Venema   +7 more
openaire   +2 more sources

The GmGT‐2F, a trihelix transcription factor, regulates seed oil content by directly activating GmAGAL transcription in soybean

Journal of Integrative Plant Biology, EarlyView.
In soybean, the trihelix transcription factor GmGT‐2F positively regulates the expression of the α‐galactosidase gene GmAGAL, thereby modulating seed oil content. The cyclophilin GmCYP2 interacts with GmGT‐2F and suppresses GmAGAL activation. Haplotype diversity analysis of GmGT‐2F, GmCYP2, and GmAGAL identified favorable haplotype combinations ...
Shuangzhe Li, Yifan Cui, Yang Liu, Mingliang Yang, Xiaoxia Wu, Qingshan Chen, Ying Zhao   +6 more
wiley   +1 more source

Prolyl isomerase Pin1 regulates mouse embryonic fibroblast differentiation into adipose cells. [PDF]

PLoS ONE, 2012
A peptidyl prolyl cis/trans isomerase, Pin1, regulates insulin signal transduction. Pin1 reduces responses to insulin stimulation by binding CRTC2 (CREB-regulated transcriptional co-activator 2) and PPARγ (peroxisome prolifereator- activated receptor γ),
Takafumi Uchida, Kengo Furumai, Tomokazu Fukuda, Hirotada Akiyama, Mika Takezawa, Tomoichiro Asano, Fumihiro Fujimori, Chiyoko Uchida   +7 more
doaj   +1 more source

Hepatotrophic effects of FK506 in dogs [PDF]

, 1991
Portacaval shunt (Eck fistula) in dogs causes hepato- cyte atrophy and organelle disruption, as well as tripling of hepatocyte mitoses. After submitting dogs to this pro-cedure, FK506 was infused into the tied-off left portal vein.
Francavilla, A, Fung, J, Mazzaferro, V, Porter, KA, Starzl, TE, Todo, S   +5 more
core   +1 more source

Novel roles of sulfur metabolism in stress‐controlled stomata aperture regulation

New Phytologist, EarlyView.
Summary Stomatal closure allows plants to conserve water by reducing transpiration during drought. Surprisingly, the assimilation of the macronutrient sulfur is intimately connected to the drought stress response. This Tansley insight will only briefly touch on the general impact of sulfate assimilation on the production of drought‐response metabolites.
Sheng‐Kai Sun, Rüdiger Hell, Markus Wirtz   +2 more
wiley   +1 more source

The prolyl isomerase Pin1 modulates development of CD8+ cDC in mice. [PDF]

PLoS ONE, 2012
Pin1 has previously been described to regulate cells that participate in both innate and adaptive immunity. Thus far, however, no role for Pin1 has been described in modulating conventional dendritic cells, innate antigen presenting cells that potently ...
Theresa J Barberi, Alexis Dunkle, You-Wen He, Luigi Racioppi, Anthony R Means   +4 more
doaj   +1 more source

Radial Spoke Proteins of \u3cem\u3eChlamydomonas\u3c/em\u3e Flagella [PDF]

, 2006
The radial spoke is a ubiquitous component of `9+2\u27 cilia and flagella, and plays an essential role in the control of dynein arm activity by relaying signals from the central pair of microtubules to the arms. The Chlamydomonas reinhardtii radial spoke
Agrin, Nathan S., Diener, Dennis R., Dienes, Jennifer M., Kamiya, Ritsu, King, Stephen M., Kohno, Takahiro, Pazour, Gregory J., Rosenbaum, Joel L., Sale, Winfield S., Witman, George B., Yang, Chun, Yang, Pinfen   +11 more
core   +1 more source

Molecular characterization of cyclophilin A-like protein from Piriformospora indica for its potential role to abiotic stress tolerance in E. coli [PDF]

, 2013
BACKGROUND: Cyclophilins (CyP), conserved in all genera, are known to have regulatory responses of various cellular processes including stress tolerance. Interestingly, CyP has a crucial role as peptidyl-prolyl cis–trans isomerases (PPIases). Our earlier
Dipesh Trivedi, Mohammed Ansari, Narendra Tuteja, Prabhjeet Singh, Tanima Dutta   +4 more
core   +1 more source

Cyclophilin A‐mediated cis/trans isomerization modulates RIN4 to control intracellular rhizobial infection in legumes

New Phytologist, EarlyView.
Summary In most legume‐rhizobium symbioses, rhizobial colonization occurs through host‐derived intracellular infection threads, which enable rhizobial recruitment while presumably modulating the host immune system to prevent rejection. To investigate post‐translational regulation of immune responses during rhizobial infection, we focused on Cyclophilin
Takashi Goto, Kasper Røjkjær Andersen, Masaru Bamba, Shusei Sato, Masayuki Sugawara, Kiwamu Minamisawa, Masayoshi Kawaguchi, Jens Stougaard, Yasuyuki Kawaharada   +8 more
wiley   +1 more source