Results 1 to 10 of about 7,517 (194)

Peptidylprolyl isomerase A guides SENP5/GAU1 DNA-lncRNA triplex generation for driving tumorigenesis [PDF]

Nature Communications
The three-stranded DNA-RNA triplex hybridization is involved in various biological processes, including gene expression regulation, DNA repair, and chromosomal stability.
Xiaoyu Zhang, Tianyi Ding, Fan Yang, Jixing Zhang, Haowen Xu, Yiran Bai, Yibing Shi, Jiaqi Yang, Chaoqun Chen, Chengbo Zhu, He Zhang   +10 more
doaj   +5 more sources

Peptidylprolyl Isomerase A (PPIA) as a Preferred Internal Control Over GAPDH and β-Actin in Quantitative RNA Analyses [PDF]

BioTechniques, 2002
A good internal control is critical in all quantitative analyses of gene expression. Levels of β-actin, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), and peptidylprolyl isomerase A (PPIA) were analyzed in 78 samples (data obtained from our laboratory
F. Feroze-Merzoug, I.M. Berquin, J. Dey, Y.Q. Chen   +3 more
exaly   +6 more sources

A Critical Role of Peptidylprolyl Isomerase A Pseudogene 22/microRNA-197-3p/Peptidylprolyl Isomerase A Axis in Hepatocellular Carcinoma [PDF]

Frontiers in Genetics, 2021
The burden of hepatocellular carcinoma (HCC) worldwide is increasing over time, while the underlying molecular mechanism of HCC development is still under exploration.
Yuwei Gu, Chao Wang, Shengsen Chen, Shengsen Chen, Jia Tang, Xiaoxiao Guo, Wei Hu, An Cui, Dian Zhang, Kangkang Yu, Mingquan Chen, Mingquan Chen   +11 more
doaj   +5 more sources

The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo [PDF]

EMBO Journal, 2003
Hsp90 is required for the normal activity of steroid receptors, and in steroid receptor complexes it is typically bound to one of the immunophilin-related co-chaperones: the peptidylprolyl isomerases FKBP51, FKBP52 or CyP40, or the protein phosphatase PP5.
Daniel L Riggs, Joyce Cheung-Flynn, Thomas Ratajczak   +2 more
exaly   +6 more sources

Peptidylprolyl isomerase C (Ppic) regulates invariant Natural Killer T cell (iNKT) differentiation in mice [PDF]

European Journal of Immunology, 2021
Abstract Peptidyl‐prolyl cis‐trans isomerase C ( Ppic ) is expressed in several bone marrow (BM) hematopoietic progenitors and in T‐cell precursors. Since the expression profile of Ppic in the hematoimmune system ...
Camila V Ramos, Afonso P Basto, Luis Graça   +2 more
exaly   +7 more sources

Upregulated Hexokinase-2 in Airway Epithelium Regulates Apoptosis and Drives Inflammation in Asthma via Peptidylprolyl Isomerase F [PDF]

Cells
Hexokinase catalyzes the first rate-limiting step glycolysis. However, the roles of hexokinase 2 (HK2) in asthma remain incompletely understood. This study aimed to investigate metabolic alterations in asthma, focusing on the expression, function and ...
Zhen Tian, Hongyan Zheng, Yan Fan, Boyu Li, Zhenli Huang, Meijia Wang, Jixian Zhang, Jianping Zhao, Shanshan Wang, Jungang Xie   +9 more
doaj   +3 more sources

Dual-Family Peptidylprolyl Isomerases (Immunophilins) of Select Monocellular Organisms [PDF]

Biomolecules, 2018
The dual-family peptidylprolyl cis-trans isomerases (immunophilins) represent a naturally occurring chimera of the classical FK506-binding protein (FKBP) and cyclophilin (CYN), connected by a flexible linker.
Sailen Barik, Barik Sailen
exaly   +5 more sources

FKBP38 Peptidylprolyl Isomerase Promotes the Folding of Cystic Fibrosis Transmembrane Conductance Regulator in the Endoplasmic Reticulum [PDF]

Journal of Biological Chemistry, 2011
FK506-binding protein 38 (FKBP38), a membrane-anchored, tetratricopeptide repeat (TPR)-containing immunophilin, associates with nascent plasma membrane ion channels in the endoplasmic reticulum (ER). It promotes the maturation of the human ether-à-go-go-related gene (HERG) potassium channel and maintains the steady state level of the cystic fibrosis ...
Yeshavanth Kumar Banasavadi-Siddegowda, Sumit Bhattacharya, David R Giovannucci   +2 more
exaly   +5 more sources

Crystallization and preliminary X-ray diffraction analysis of the peptidylprolyl isomerase Par27 ofBordetella pertussis [PDF]

Acta Crystallographica Section F: Structural Biology Communications, 2008
Proteins with both peptidylprolyl isomerase (PPIase) and chaperone activities play a crucial role in protein folding in the periplasm of Gram-negative bacteria. Few such proteins have been structurally characterized and to date only the crystal structure of SurA from Escherichia coli has been reported.
Hélène Hodak, Bernard Clantin, Françoise Jacob-Dubuisson   +2 more
exaly   +5 more sources

Identification of stable normalization genes for quantitative real-time PCR in porcine articular cartilage

Journal of Animal Science and Biotechnology, 2012
Background Expression levels for genes of interest must be normalized with an appropriate reference, or housekeeping gene, to make accurate comparisons of quantitative real-time PCR results.
McCulloch Ryan S, Ashwell Melissa S, O’Nan Audrey T, Mente Peter L   +3 more
doaj   +4 more sources