Results 71 to 80 of about 684,699 (287)

Prominence in Indonesian Stress, phrases, and boundaries

open access: yesWacana: Journal of the Humanities of Indonesia, 2009
Many (Western) languages have word-based stress, which entails that one, predictable syllable per word is more prominent than all the other syllables in that word. Some linguists claim that such stresses also occur in Indonesian.
Ellen van Zanten, Rob Goedemans
doaj   +1 more source

Open questions on prominences from coordinated observations by IRIS, Hinode, SDO/AIA, THEMIS, and the Meudon/MSDP

open access: yes, 2014
Context. A large prominence was observed on September 24, 2013, for three hours (12:12 UT -15:12 UT) with the newly launched (June 2013) Interface Region Imaging Spectrograph (IRIS), THEMIS (Tenerife), the Hinode Solar Optical Telescope (SOT), the Solar ...
A. López Ariste   +7 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Athletic Identity Measurement Scale-3rd Generation (AIMS-3G) Reliabilities and Factor Structures in Competing Athletes

open access: yesYouth
The AIMS-3G was developed to expand and reconceptualize previous measures and conceptualizations of athletic identity. Although the AIMS-3G has appeared in research, comprehensive tests of its validity and reliability had not extended beyond the initial ...
Marc Lochbaum   +4 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The Thermal Instability of Solar Prominence Threads

open access: yes, 2011
The fine structure of solar prominences and filaments appears as thin and long threads in high-resolution images. In H-alpha observations of filaments, some threads can be observed for only 5 - 20 minutes before they seem to fade and eventually disappear,
Arregui   +22 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Prosodic focus in English vs. French: A scope account

open access: yesGlossa, 2018
We compare the use of prosodic prominence in English and French to convey focus. While previous studies have found these languages, and Germanic vs. Romance more generally, to differ in their use of prominence to encode focus (e.g., Ladd 1990; 1996; 2008;
Heather Goad   +2 more
doaj   +2 more sources

Non-thermal line-broadening in solar prominence

open access: yes, 2015
We show that the line broadening in quiescent solar prominences is mainly due to non-thermal velocities. We have simultaneously observed a wide range of optically thin lines in quiescent prominences, selected for bright and narrow Mg\,b emission without ...
Stellmacher, Goetz, Wiehr, Eberhard
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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