Results 61 to 70 of about 22,877 (292)

Wnt/β-catenin signaling and Msx1 promote outgrowth of the maxillary prominences

Frontiers in Physiology, 2012
Facial morphogenesis requires a series of precisely orchestrated molecular events to promote the growth and fusion of the facial prominences. Cleft palate (CP) results from perturbations in this process.
Marie eMedio, Erika eYeh, Antoine ePopelut, Sylvie eBabajko, Ariane eBerdal, Ariane eBerdal, Jill eHelms   +6 more
doaj   +1 more source

Spatial and temporal analysis of gene expression during growth and fusion of the mouse facial prominences. [PDF]

PLoS ONE, 2009
Orofacial malformations resulting from genetic and/or environmental causes are frequent human birth defects yet their etiology is often unclear because of insufficient information concerning the molecular, cellular and morphogenetic processes responsible
Weiguo Feng, Sonia M Leach, Hannah Tipney, Tzulip Phang, Mark Geraci, Richard A Spritz, Lawrence E Hunter, Trevor Williams   +7 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Dynamics, thermodynamics, and fine structure of virtual erupting filaments

Astronomy & Astrophysics
Context. It is not fully understood why some solar filaments erupt, whereas others do not. Filaments that erupt typically undergo a slow rise, followed by an acceleration phase; this transition requires further investigation.
Donné D., Zhou Y., Cremades H., Keppens R.   +3 more
doaj   +1 more source

Scutigera tancitarona Chamberlin, nuevo sinónimo júnior de Dendrothereua linceci (Wood) (Scutigeromorpha: Scutigeridae)

Revista Chilena de Entomología, 2019
Scutigera tancitarona is designated as a junior synonym of Dendrothereua linceci based on morphological features of tergal prominences and female gonopod.
Fabio G. Cupul-Magaña
doaj   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Radio, X-ray, and extreme ultraviolet signatures of internal and external reconnection of an erupting flux rope

Astronomy & Astrophysics
Aims. We aim to interpret and relate features observed in gigahertz radio, extreme UV (EUV), and X-ray emissions during a filament eruption at the start of a solar flare on 2 April 2022. Methods.
Kašparová Jana, Dudík Jaroslav, Karlický Marian, Zemanová Alena, Massa Paolo, Krucker Samuel, Schuller Frédéric, Rybák Ján   +7 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Velocity field of an active region filament from GRIS infrared He I and IRIS ultraviolet observations

Astronomy & Astrophysics
Context. Plasma flow measurements in solar active region filaments are rare, particularly in the infrared and ultraviolet ranges that probe the chromosphere and transition region.
Murabito M., Andretta V., Parenti S., Kuckein C., González Manrique S. J., Lezzi S. M., Guglielmino S. L.   +6 more
doaj   +1 more source