Results 81 to 90 of about 12,284 (241)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
High-resolution Observation of Solar Prominence Plumes Induced by Enhanced Spicular Activity
The Astrophysical Journal LettersSolar prominences are the most prominent large-scale structures observed above the solar limb in emission in chromospheric lines but in absorption in coronal lines. At the bottom of prominences often appears a bubble, with plumes occasionally rising from
Wensi Wang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Automated detection of EUV prominences
, 2006 We present methods to detect automatically off-limb prominences in the extreme ultraviolet (EUV), using synoptic images taken by the extreme-ultraviolet imaging telescope (EIT) on board SOHO.
Foullon, C. (Claire) +1 more
core +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Elemental composition in quiescent prominences
, 2019 Context. The first ionization potential (FIP) bias is currently used to trace the propagation of solar features ejected by the wind and solar eruptions (coronal mass ejections). The FIP bias also helps us to understand the formation of prominences, as it
G. Del Zanna +5 more
core +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
, 1984 We have studied rotation in non-eruptive limb prominences; in most cases dopplergrams could be used to confirm proper motion measurements. In some cases part of the prominence rotates; in the others, the entire body is in rotation. Velocities of 15–75 km
Zirin, H., Liggett, M.
core
3D numerical simulations of oscillations in solar prominences [PDF]
[eng] Context. Oscillations in solar prominences are a frequent phenomenon, and they have been the subject of many studies. A full understanding of the mechanisms that drive them and their attenuation has not been reached yet, however. Aims.
Jaume Terradas Calafell +1 more
core +1 more source