Results 91 to 100 of about 22,877 (292)

Near-Limb Zeeman and Hanle Diagnostics

, 2013
"Weak" magnetic-field diagnostics in faint objects near the bright solar disk are discussed in terms of the level of non-object signatures, in particular, of the stray light in telescopes.
A.D. Romanov, B. Lyot, B.A. Ioshpa, D. Socker, E. Tandberg-Hanssen, E. Tandberg-Hanssen, G. Newkirk Jr., G.M. Nikolskii, G.M. Nikolskij, G.Y. Smol’kov, H. Lin, H. Nagaoka, H. Peter, H. Zirin, I. Kim, I.S. Kim, I.S. Kim, I.S. Kim, J. Chae, J. Wagner, J.M. Malville, J.W. Harvey, O. En den, R.G. Athay, R.H. Lee, R.H. Lee, R.J. Terrile, S. Keil, S. Tomczyk, T.R. Rimmele, V.S. Bashkirtsev   +30 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Statistical Analyses of Solar Prominences and Active Region Features in 304 Å Filtergrams Detected via Deep Learning

The Astrophysical Journal Supplement Series
Solar active regions (ARs) are areas on the Sun with very strong magnetic fields where various activities take place. Prominences are one of the typical solar features in the solar atmosphere, whose eruptions often lead to solar flares and coronal mass ...
T. Zhang, Q. Hao, P. F. Chen
doaj   +1 more source

Tfap2a-dependent changes in mouse facial morphology result in clefting that can be ameliorated by a reduction in Fgf8 gene dosage

Disease Models & Mechanisms, 2015
Failure of facial prominence fusion causes cleft lip and palate (CL/P), a common human birth defect. Several potential mechanisms can be envisioned that would result in CL/P, including failure of prominence growth and/or alignment as well as a failure of
Rebecca M. Green, Weiguo Feng, Tzulip Phang, Jennifer L. Fish, Hong Li, Richard A. Spritz, Ralph S. Marcucio, Joan Hooper, Heather Jamniczky, Benedikt Hallgrímsson, Trevor Williams   +10 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Source Regions of Coronal Mass Ejections

, 2001
Observations of the solar corona with the Large Angle Spectrometric Coronograph (LASCO) and Extreme ultraviolet Imaging Telescope (EIT) instruments on the Solar and Heliospheric Observatory (SOHO) provide an unprecedented opportunity to study coronal ...
Delannee C., K. P. Dere, Prasad Subramanian   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Structure and Dynamics of Erupting Solar Prominences Using the Rolling Hough Transform: Toward a Feature-oriented Classification

The Astrophysical Journal
The classification of solar prominences has proven to be challenging, due to their diverse morphologies and dynamical behavior. Complexity is heightened when considering eruptive prominences, where the dynamics demand methods capable of capturing ...
Harry Birch, Stéphane Régnier
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

High-resolution Observation of Solar Prominence Plumes Induced by Enhanced Spicular Activity

The Astrophysical Journal Letters
Solar prominences are the most prominent large-scale structures observed above the solar limb in emission in chromospheric lines but in absorption in coronal lines. At the bottom of prominences often appears a bubble, with plumes occasionally rising from
Wensi Wang, Rui Liu, Runbin Luo, Xiaoli Yan   +3 more
doaj   +1 more source