Results 91 to 100 of about 12,284 (241)
A Robust Deep Learning Framework for Prominence Detection through Composite Feature Representations
The Astrophysical JournalSolar prominences are dynamic structures suspended within the solar corona and are a manifestation of solar activity. Their evolution includes eruptions linked to coronal mass ejections, making their detection critical for space weather monitoring and ...
Harry Birch +2 more
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
New perspectives on solar prominences
, 2011 Recent observations of prominences obtained with high spatial and temporal resolution instruments, on board satellites (Hinode, SDO) as well as on the ground (SST) have provided very intriguing movies and open a new area for understanding the nature of ...
Schmieder, Brigitte +3 more
core +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
A Dynamical Model of Solar Prominences with Current Sheet [PDF]
Recent observations of solar prominences show that slow upward motions ( ≌ 1 kms^ ) occur through quiescent prominences and a fast input of material with horizontal motions ( ≌ 5 kms^ ) occurs at both edges of prominences.
鷲見, 治一, 坂井, 純一
core +1 more source
Observation of Persistent Propagating Waves in a Solar Prominence
The Astrophysical JournalSpectropolarimetric observation of a quiescent prominence was performed in He i 1083 nm. With the slit of the spectrograph fixed on the prominence, we obtained a time series of Stokes profiles for a duration of 108 minutes with a cadence of 8 s.
Kiyoshi Ichimoto +8 more
doaj +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Forming Prominences Accounting for Partial Ionization Effects
The Astrophysical JournalOne of the most striking structures in the solar atmosphere are prominences, predominantly coronal structures, with thermodynamic conditions that vary from chromospheric internally to the corona that surrounds them.
V. Jerčić +2 more
doaj +1 more source