Motif Discovery through Predictive Modeling of Gene Regulation
We present MEDUSA, an integrative method for learning motif models of transcription factor binding sites by incorporating promoter sequence and gene expression data.
A. Battle +15 more
core +2 more sources
Transcriptional regulation of the hepatitis B virus large surface antigen gene [PDF]
Hepatitis B virus (HBV) is a hepatotropic virus of highly restricted host range and tissue specificity. Although the mechanisms governing this tropism are not fully understood, it is likely that restrictions occur at multiple steps in the viral life ...
Raney, Anneke K.
core
Association of TERT Promoter Mutation, But Not BRAF Mutation, With Increased Mortality in PTC [PDF]
Jonathan R. George +6 more
openalex +1 more source
Synergistic Binding of bHLH Transcription Factors to the Promoter of the Maize NADP-ME Gene Used in C4 Photosynthesis Is Based on an Ancient Code Found in the Ancestral C3 State [PDF]
Ana Rita Borba +11 more
openalex +1 more source
The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing. [PDF]
Transcriptional regulation in eukaryotes occurs at promoter-proximal regions wherein transcriptionally engaged RNA polymerase II (Pol II) pauses before proceeding toward productive elongation.
Ablondi, Eileen +20 more
core +1 more source
The Distal and Proximal Regulatory Regions of the Involucrin Gene Promoter have Distinct Functions and Are Required for In Vivo Involucrin Expression [PDF]
James F. Crish +4 more
openalex +1 more source
CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency
Navneet Matharu +9 more
openalex +2 more sources

