Results 171 to 180 of about 2,113,360 (356)

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

Molecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock, Lina Benzien, Sandra Lange, Maja Huehns, Alexandra Runge, Catrin Roolf, Anett Sekora, Gudrun Knuebel, Hugo Murua Escobar, Christian Junghanss, Anna Richter   +10 more
wiley   +1 more source

XII. A letter from Dr. Ducarel, F. R. S. and F. S. A. to William Watson, M. D. F. R. S. upon the early cultivation of botany in England; and some particulars about John Tradescant, a great promoter of that science, as well as natural history, in the last century, and gardener to King Charles I. [PDF]

Andrew Coltee Ducarel, Andrew Coltee Ducarel   +1 more
openalex   +1 more source

Endogenous Carbohydrates, Root Promoters, and Root Inhibitors in Easy- and Difficuit-to-Root Date Palm (Phoenix dactylifera L.) Offshoots1,2 [PDF]

, 1974
O. Reuveni, I. Adato
openalex   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

Molecular Characterization and Expression Profiles of Myrosinase Gene (RsMyr2) in Radish (Raphanus sativus L.)

Journal of Integrative Agriculture, 2014
Myrosinase is a defense-related enzyme and is capable of hydrolyzing glucosinolates into a variety of compounds, some of which are toxic to pathogens and herbivores.
Yan PAN, Yuan-yuan XU, Xian-wen ZHU, Zhe LIU, Yi-qin GONG, Liang XU, Mao-yong GONG, Li-wang LIU   +7 more
doaj  

(288)Oxydation of Lubricating Oils. X. Repeated Oxydation of the Mineral Oil in the Presence of Promoter.

, 1953
Yasuo Matsuki, Osamu Watanabe
openalex   +2 more sources

New genes and promoters suggested by the DNA sequence near the end of the coliphage T7 early operon [PDF]

, 1979
John C. Boothroyd, Richard S. Hayward
openalex   +1 more source

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

Molecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti, Shingo Inagaki, Tuyen Thuy Bich Ho, Akihiro Seki, Keiko Yoshida, Kosuke Satomura, Yoshio Sakai, Shuichi Kaneko, Taro Yamashita   +8 more
wiley   +1 more source

Endogenous Promoter and Inhibitor Levels in Lilium longiflorum Bulbs1 [PDF]

, 1975
Wei Lin, Harold F. Wilkins, M. L. Brenner   +2 more
openalex   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source