In silico analysis of transcription factor binding sites in promoters of germin-like protein genes in rice [PDF]
Germins (GERs) and germin-like proteins (GLPs) play important roles in responses to various stresses; however, their function is still not fully understood. Significant insight into their function can be obtained by analyzing their promoters. In
Ilyas Muhammad +2 more
doaj +1 more source
Promoting human promoters [PDF]
Mol Syst Biol. 2: 2006.0030 The effect of transcription factors on human gene expression can now be quantified owing to a new computational approach. The method was successfully applied to the cases of the cell cycle program, and for liver‐specific gene expression. Transcriptional regulation of gene expression plays a major role in the acquisition of
Furman, Itay, Pilpel, Yitzhak
openaire +1 more source
Promoter-enhancer interactions at TDRD9 locus in nasal epithelial cells.
Promoter-to-enhancer chromatin interactions captured by Hi-C in nasal epithelial cells from URECA at age 11 are displayed as grey arcs. SNPs associated with FEV1 (p-5) are marked by blue lines in the top row according to their genomic position on ...
Deepa Rastogi (6635723) +26 more
core +1 more source
The promoter from SlREO, a highly-expressed, root-specific Solanum lycopersicum gene, directs expression to cortex of mature roots [PDF]
Root-specific promoters are valuable tools for targeting transgene expression, but many of those already described have limitations to their general applicability.
Wright, Carole +5 more
core +1 more source
Trichostatin A induces 5-lipoxygenase promoter activity and mRNA expression via inhibition of histone deacetylase 2 and 3 [PDF]
The 5-lipoxygenase (5-LO) is the key enzyme in the formation of leukotrienes. We have previously shown that the histone deacetylase (HDAC) inhibitor trichostatin A (TSA) activates 5-LO transcription via recruitment of Sp1, Sp3 and RNA polymerase II to ...
Julia Metzner +13 more
core +1 more source
O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation [PDF]
Background: We analyzed prospectively whether MGMT (O(6)-methylguanine-DNA methyltransferase) mRNA expression gains prognostic/predictive impact independent of MGMT promoter methylation in malignant glioma patients undergoing radiotherapy with ...
Kreth Simone +35 more
core +1 more source
Levulinic Acid-Inducible and Tunable Gene Expression System for Methylorubrum extorquens
Methylorubrum extorquens AM1 is an efficient platform strain possessing biotechnological potential in formate- and methanol-based single carbon (C1) bioeconomy.
Chandran Sathesh-Prabu +3 more
doaj +1 more source
A mutation in a functional Sp1 binding site of the telomerase RNA gene (hTERC) promoter in a patient with Paroxysmal Nocturnal Haemoglobinuria [PDF]
Background<br/><br/> Mutations in the gene coding for the RNA component of telomerase, hTERC, have been found in autosomal dominant dyskeratosis congenita (DC) and aplastic anemia.
Ulku, B. +47 more
core +2 more sources
In response to the escalating demand for cleaner energy sources, this study investigates the potential of carefully selected functionalized graphene-based materials for enhancing hydrogen sulphide (H2S) removal in fuel streams, utilizing semi-empirical ...
Toyese Oyegoke +3 more
doaj +1 more source
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld +5 more
wiley +1 more source

