Results 51 to 60 of about 942,561 (267)

Optimized barley phytase gene expression by focused FIND-IT screening for mutations in cis-acting regulatory elements

Frontiers in Plant Science
IntroductionInduced modification of plant gene expression is of both fundamental and applied importance. Cis-acting regulatory elements (CREs) are major determinants of the spatiotemporal strength of gene expression.
Claus Krogh Madsen, Charles Alistair Brearley, Jesper Harholt, Henrik Brinch-Pedersen   +3 more
doaj   +1 more source

Inoculação de sementes de milho utilizando o Trichoderma harzianum como promotor de crescimento Corn seed inoculation using Trichoderma harzianum as a growth promoter

Ciência e Agrotecnologia, 2004
Conduziu-se este trabalho com o objetivo de estudar o efeito do fungo Trichoderma harzianum como promotor de crescimento de sementes de milho tratadas com diferentes fungicidas.
Maria de Lourdes Resende, João Almir de Oliveira, Renato Mendes Guimarães, Renzo Garcia Von Pinho, Antônio Rodrigues Vieira   +4 more
doaj   +1 more source

Tracking Health Related Quality of Life From Diagnosis to Follow‐Up Among Australian Children With Acute Lymphoblastic Leukaemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukaemia (ALL) is one of the most treatable forms of paediatric cancer; however, there is a substantial burden of treatment‐related toxicities (TRTs). In addition, the long‐term changes in children's health‐related quality of life (HRQoL) due to toxic treatments are not well understood.
Clare Ghows, Clarissa E. Schilstra, Karen McCleary, Nancy E. Briggs, Rishi S. Kotecha, Richard De Abreu Lourenco, Shanti Ramachandran, Ruelleyn Cockcroft, Rachel Conyers, Siobhan Cross, Luciano Dalla‐Pozza, Peter Downie, Tamas Revesz, Michael Osborn, Frank Alvaro, Claire E. Wakefield, Glenn M. Marshall, Toby Trahair, Marion K. Mateos, Joanna E. Fardell   +19 more
wiley   +1 more source

Mechanisms and Functions of the RNA Polymerase II General Transcription Machinery during the Transcription Cycle

Biomolecules
Central to the development and survival of all organisms is the regulation of gene expression, which begins with the process of transcription catalyzed by RNA polymerases.
Stephen R. Archuleta, James A. Goodrich, Jennifer F. Kugel   +2 more
doaj   +1 more source

Association Between the Methylation Statuses at CpG Sites in the Promoter Region of the SLCO1B3, RNA Expression and Color Change in Blue Eggshells in Lushi Chickens

Frontiers in Genetics, 2019
The formation mechanism underlying the blue eggshell characteristic has been discovered in birds, and SLCO1B3 is the key gene that regulates the blue eggshell color.
Zhuanjian Li, Zhuanjian Li, Tuanhui Ren, Wenya Li, Yu Zhou, Ruili Han, Ruili Han, Hong Li, Hong Li, Ruirui Jiang, Ruirui Jiang, Fengbin Yan, Fengbin Yan, Guirong Sun, Guirong Sun, Xiaojun Liu, Xiaojun Liu, Yadong Tian, Yadong Tian, Xiangtao Kang, Xiangtao Kang   +20 more
doaj   +1 more source

Bridging the Gap in Neuroblastoma Care: Consensus‐Based Statements With Recommendations for Improved Patient and Caregiver Experiences

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma's complex, heterogeneous biology poses significant diagnostic and therapeutic challenges, often requiring caregivers to absorb complex information and participate in time‐sensitive decisions. However, caregivers often feel unprepared to evaluate options.
Vickie Buenger, Joseph Bauer, Jennifer Diamond, Maggie Fader, Shae Hansen, Jacqueline M. Kraveka, Johanna Schoen, Amber Shearer, Dena Sherwood   +8 more
wiley   +1 more source

DeePromoter: Robust Promoter Predictor Using Deep Learning

Frontiers in Genetics, 2019
The promoter region is located near the transcription start sites and regulates transcription initiation of the gene by controlling the binding of RNA polymerase.
Mhaned Oubounyt, Zakaria Louadi, Hilal Tayara, Kil To Chong   +3 more
doaj   +1 more source

Promoting Adipose Specificity: The Adiponectin Promoter [PDF]

Endocrinology, 2010
In the modern obesogenic environment, obesity, insulin resistance and type 2 diabetes mellitus are becoming a global epidemic. At the organismal level, obesity is causally linked to the metabolic dysfunction of energy balance and homeostasis in the adipose tissue (reviewed in Refs. 1–3).
openaire   +2 more sources

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Persistent transgene expression in peripheral tissues one year post intravenous and intramuscular administration of AAV vectors containing the alphaherpesvirus latency-associated promoter 2

Frontiers in Virology
Significant progress has been made in enhancing recombinant adeno-associated virus (rAAV) for clinical investigation. Despite its versatility as a gene delivery platform, the inherent packaging constraint of 4.7 kb imposes restrictions on the range of ...
Carola J. Maturana, Esteban A. Engel
doaj   +1 more source