Results 81 to 90 of about 1,233,859 (314)

The human adenovirus 5 L4 promoter is activated by cellular stress response protein p53 [PDF]

open access: yes, 2013
During adenovirus infection, the emphasis of gene expression switches from early genes to late genes in a highly regulated manner. Two gene products, L4-22K and L4-33K, contribute to this switch by activating the Major Late Transcription Unit (MLTU) and ...
Leppard, Keith, Wright, Jordan
core   +1 more source

DeePromoter: Robust Promoter Predictor Using Deep Learning

open access: yesFrontiers in Genetics, 2019
The promoter region is located near the transcription start sites and regulates transcription initiation of the gene by controlling the binding of RNA polymerase.
Mhaned Oubounyt   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Persistent transgene expression in peripheral tissues one year post intravenous and intramuscular administration of AAV vectors containing the alphaherpesvirus latency-associated promoter 2

open access: yesFrontiers in Virology
Significant progress has been made in enhancing recombinant adeno-associated virus (rAAV) for clinical investigation. Despite its versatility as a gene delivery platform, the inherent packaging constraint of 4.7 kb imposes restrictions on the range of ...
Carola J. Maturana, Esteban A. Engel
doaj   +1 more source

MhYTP1 and MhYTP2 from Apple Confer Tolerance to Multiple Abiotic Stresses in Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2017
The first YTH domain-containing RNA binding protein (YTP) was found in rat, where it was related to oxidative stress. Unlike characterizations in yeast and animals, functions of plant YTPs are less clear. Malus hupehensis (Pamp.) Rehd.
Na Wang   +8 more
doaj   +1 more source

Functional Characterization of a Dual Enhancer/Promoter Regulatory Element Leading Human CD69 Expression

open access: yesFrontiers in Genetics, 2020
The CD69 gene encodes a C-type lectin glycoprotein with immune regulatory properties which is expressed on the cell surfaces of all activated hematopoietic cells.
Jennifer Redondo-Antón   +6 more
doaj   +1 more source

Promoting Adipose Specificity: The Adiponectin Promoter [PDF]

open access: yesEndocrinology, 2010
In the modern obesogenic environment, obesity, insulin resistance and type 2 diabetes mellitus are becoming a global epidemic. At the organismal level, obesity is causally linked to the metabolic dysfunction of energy balance and homeostasis in the adipose tissue (reviewed in Refs. 1–3).
openaire   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Promoter Working Group 7082

open access: yes, 2007
: Promoter working group was created in september 1992 under the umbrella, and with a three-years funding, of the Esprit III program in Basic Research. Its main objective is to strengthen and organize European software process modelling research.
J C Derniame, Promoter Final, A Synopsis
core  

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