Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Motivation to move fast, motivation to wait and see: The association of prevention and promotion focus with clinicians' implementation of the JNC-7 hypertension treatment guidelines. [PDF]
Sanders M +7 more
europepmc +1 more source
'Promotion focus' facilitates resilient problem solving
Masayoshi Shigemori +2 more
openaire +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
JOB MATCHING QUALITY EFFECTS OF EMPLOYMENT PROMOTION MEASURES FOR PEOPLE WITH DISABILITIES [PDF]
In this article, we evaluate the influence that employment promotion measures designed for disabled people have on the latter’s job matching quality through the use of matching analysis.
Fernando Munoz-Bullon, Miguel A. Malo
core
Pengaruh Harga Dan Promosi Terhadap Keputusan Konsumen Dalam Pembelian Cat Merek Mowilek Di Jakarta [PDF]
This study aimed to determine the effect of price perception on purchase decisions and promotion of Mowilex paint,Exogenous variables were examined in this study is the perception of price and promotion variables.
Yosep, L. (Lim)
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The EU and Bosnia and Herzegovina: Democracy promotion within the limits of the "ethnic conflict" paradigm [PDF]
Seeking to contribute to the emerging debate about the substance of EU democracy promotion policies, this paper takes as its focus Bosnia and Herzegovina, where the EU‟s current democracy promotion efforts are primarily focused on reform of the country‟s
Cooley, Laurence
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The communication of social norms is a strong driver of behavior and is therefore recommended as a persuasive tool for tax compliance. However, the evidence on the influence of social norms on tax behavior remains inconclusive. Ambiguous results could be
Janet Kleber +3 more
doaj +1 more source

