Results 131 to 140 of about 1,663,973 (301)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Employment promotion measures and the quality of the job match for persons with disabilities [PDF]
We evaluate the influence that employment promotion measures and labour market intermediation services addressed to disabled individuals have on the latter’s quality of the job match through the use of matching analysis techniques. Our focus is placed on
Fernando Muñoz-Bullón +1 more
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Classification of Empirical Work on Sales Promotion: A Synthesis for Managerial Decision Making [PDF]
Sales Promotion activities have gained strategic focus as markets are getting complex and competitive. Key managerial concerns in this area are budget allocation across elements of promotions as well as trade vis.
Mehta Bijal, Vyas Preeta H
core
The EU and Bosnia and Herzegovina: Democracy promotion within the limits of the "ethnic conflict" paradigm [PDF]
, 2011 Seeking to contribute to the emerging debate about the substance of EU democracy promotion policies, this paper takes as its focus Bosnia and Herzegovina, where the EU‟s current democracy promotion efforts are primarily focused on reform of the country‟s
Cooley, Laurence
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
BMC PsychologyThis present research aims to clarify the intricate conjunction of enterprise social media (ESM) utilization and employee agility with a main focus on uncovering the underlying mechanisms that work through the mediating influence of work engagement and ...
Yilinna Bao +3 more
doaj +1 more source
Evaluating an Online Family Assessment Activity: A Focus on Diversity and Health Promotion [PDF]
, 2016 This article describes the development, implementation and evaluation of a family assessment activity that was designed for a transition course in an RN-BSN program.
Jones, Melissa, Smith, Paul
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source