Results 101 to 110 of about 4,804,928 (276)
DinamisiaChatGPT, a widely used Large Language Model (LLM), enhances productivity in various sectors, including education. However, its extensive usage often lacks proficiency in writing effective prompts, resulting in less optimal, biased, and hallucinated ...
Setio Basuki +5 more
doaj +1 more source
From Prompt Engineering to Prompt Science with Humans in the Loop
Communications of the ACMCan prompt engineering be made more reliable, verifiable, and generalizable?
openaire +3 more sources
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The Impact of Prompting Techniques on the Security of the LLMs and the Systems to Which They Belong
Applied SciencesLarge language models have demonstrated impressive capabilities. The recent research conducted in the field of prompt engineering showed that their base performance is just a glimpse of their full abilities.
Teodor Ivănușcă, Cosmin-Iulian Irimia
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Stress detection through prompt engineering with a general-purpose LLM
Acta PsychologicaAdvancements in large language models (LLMs) have opened new avenues for mental health monitoring through social media analysis. In this study, we present an iterative prompt engineering framework that significantly enhances the performance of the ...
Nima Esmi +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
智能科学与技术学报Large language models and vision-language models have demonstrated significant potential in various downstream applications, making it become a research hotspot.
HUANG Jun +8 more
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source