Results 111 to 120 of about 370,431 (273)

The Impact of Prompting Techniques on the Security of the LLMs and the Systems to Which They Belong

Applied Sciences
Large language models have demonstrated impressive capabilities. The recent research conducted in the field of prompt engineering showed that their base performance is just a glimpse of their full abilities.
Teodor Ivănușcă, Cosmin-Iulian Irimia
doaj   +1 more source

Conversational Prompt Engineering

Prompts are how humans communicate with LLMs. Informative prompts are essential for guiding LLMs to produce the desired output. However, prompt engineering is often tedious and time-consuming, requiring significant expertise, limiting its widespread use.
Ein-Dor, Liat, Toledo-Ronen, Orith, Spector, Artem, Gretz, Shai, Dankin, Lena, Halfon, Alon, Katz, Yoav, Slonim, Noam   +7 more
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Assistance in Preparing Engineering Prompts for Muhammadiyah School Teachers to Optimize the Use of ChatGPT in the World of Education

Dinamisia
ChatGPT, a widely used Large Language Model (LLM), enhances productivity in various sectors, including education. However, its extensive usage often lacks proficiency in writing effective prompts, resulting in less optimal, biased, and hallucinated ...
Setio Basuki, Mahar Faiqurrahman, Gita Indah Marthasari, Rizky Indrabayu, Fatimatus Zachra, Nico Ardia Effendy   +5 more
doaj   +1 more source

LES modelling of nitric oxide (NO) formation in a propane-air turbulent reacting flame [PDF]

, 2014
Large Eddy Simulation (LES) technique is applied to investigate the nitric oxide (NO) formation in the propane-air flame inside a cylindrical combustor.
Paul, Manosh C., Paul, Sreebash C., Saha, Suvash C.   +2 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Stress detection through prompt engineering with a general-purpose LLM

Acta Psychologica
Advancements in large language models (LLMs) have opened new avenues for mental health monitoring through social media analysis. In this study, we present an iterative prompt engineering framework that significantly enhances the performance of the ...
Nima Esmi, Asadollah Shahbahrami, Yasaman Nabati, Bita Rezaei, Georgi Gaydadjiev, Peter de Jonge   +5 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

SkipFlow: Incorporating Neural Coherence Features for End-to-End Automatic Text Scoring

, 2017
Deep learning has demonstrated tremendous potential for Automatic Text Scoring (ATS) tasks. In this paper, we describe a new neural architecture that enhances vanilla neural network models with auxiliary neural coherence features. Our new method proposes
Hui, Siu Cheung, Phan, Minh C., Tay, Yi, Tuan, Luu Anh   +3 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source