Results 61 to 70 of about 4,150,880 (292)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Obturator Nerve Palsy in a Patient with Fascio Scapulo Humeral Dystrophy Undergoing Scapulopexy in Prone Position: A Rare Occurrence [PDF]
All surgical positions carry some degree of position-related risks. The most common serious positional injuries are peripheral nerve injuries. We present a case of 23 years old man with obturator nerve injury with clinically evident sequelae following a ...
Hussain Khan Zahid+2 more
doaj +2 more sources
Prone position and APRV for severe hypoxemia in COVID-19 patients: The role of perfusion
There have been confusion and contradiction on how to best manage patients with acute respiratory failure secondary to Corona virus disease-2019 (COVID-19). Recent report suggested two different phenotypes of patho-physiology (type L and type H).
Ehab G. Daoud+2 more
doaj +1 more source
Internal Jugular Vein Cannulation in Prone Position
Since 1970, prone decubitus (PD) has been used as adjuvant therapy to treat severe hypoxia in patients with acute respiratory distress syndrome (ARDS), and now with the COVID-19 pandemic, its use has become widespread in ICUs.
Ibzan J. Salvador-Ibarra, MD
doaj +1 more source
Background: To assess the feasibility, image quality and diagnostic value of contrast-enhanced breast magnetic resonance imaging (MRI) performed in a supine compared to a prone position.
A. Fausto+9 more
semanticscholar +1 more source
Anesthesia in the prone lithotomy position [PDF]
To the Editor: We present our experience of the anesthetic management of patients in the rarely used prone lithotomy position (Figure). During surgery, the prone position, if correctly applied, ensures free abdominal movement, is not associated with adverse effects on respiratory mechanics and improves lung volume and oxygenation.1,2 The lithotomy ...
Chandra Kant Pandey, Shashi Srivastava
openaire +2 more sources
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan+2 more
wiley +1 more source
Three-dimensional conformal breast irradiation in the prone position
The prone position can be used for the planning of adjuvant radiotherapy after conservative breast surgery in order to deliver less irradiation to lung and cardiac tissue.
C. Kurtman+3 more
doaj +1 more source