Results 111 to 120 of about 247,842 (346)
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Chinese-American pronunciation versus standard American pronunciation
Nonpartisan Education Review, 2014 no ...
Robert Oliphant
doaj
Echo of the Quranic Statement, Grammar & Rhetoric of Abdul Qaher Jarjani Al Baqara Chapter as an Example [PDF]
دراسات في اللغة العربيّة وآدابهاWhen addressing the Quranic studies, huge tradition & illustrations are produced, among which, Abdul Qaher Jarjani’s work was profound. He paid great attention to the Quran with holistic view based on his linguistic theory.He deeply pondered his ...
SawsanAhmad Nabresi, Mohammad Al_Rabaa
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
AN ERROR ANALYSIS OF PHONEMESIN READING – ALOUD ACTIVITY \ud PRODUCED BY THE FIRSTSEMESTER STUDENTS OF ENGLISH \ud DEPARTMENT, MUHAMMADIYAH UNIVERSITY OF MALANG [PDF]
, 2007 This study was conducted to analyze the error or phonemes in reading aloud activity produced by the first semester students of English Department of Muhammdiyah University of Malang. The design that the researcher used is descriptive qualitative research.
SUSILAWATI, FITRI
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Minimizing word error rate in a dyslexic reading-oriented ASR engine using phoneme refinement and alternative pronunciation [PDF]
, 2010 Little attention has been given to detecting miscues in the text space read by dyslexic children over an automatic speech recognition (ASR) engine. In an ASR system, the miscues are represented by word error rate (WER) and miscue detection rate (MDR). At
Husni, Husniza, Jamaludin, Zulikha
core