Results 71 to 80 of about 242,626 (288)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

PERMASALAHAN PENGUCAPAN BUNYI VOKAL BAHASAINGGRIS [PDF]

open access: yes, 2015
The English language learners might have problems in the pronunciation of English vowel sounds. It is assumed that the sound system of the mother tongue, in this case Javanese has, to some extent, affected the pronunciation of English sounds.
Wibowo , Agus Hari
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

THE INFLUENCE OF BAHASA MANDAR TOWARDS STUDENTS’ ENGLISH PRONUNCIATION [PDF]

open access: yes, 2016
Pronunciation is one of language elements which plays an important role. By having fluentpronunciation, it makes communication more intelligible. This research analyzes the influenceof Bahasa Mandar towards students’ English pronunciation. It focuses on
Uswatunnisa , Uswatunnisa
core  

Learning English pronunciation in and outside the classroom: Psychopedagogic considerations [PDF]

open access: yes, 2013
Udostępnienie publikacji Wydawnictwa Uniwersytetu Łódzkiego finansowane w ramach projektu „Doskonałość naukowa kluczem do doskonałości kształcenia”. Projekt realizowany jest ze środków Europejskiego Funduszu Społecznego w ramach Programu Operacyjnego ...
Majer, Halina
core   +1 more source

A study of voiceless inter-dental fricative [θ], [ð] sounds and alveolar liquid [r] sound among Chinese learners of English at a higher educational institution in Malaysia

open access: yesJournal of Applied Studies in Language, 2019
This study aims to investigate the pronunciation mistakes in English in accordance with the phonetic study of voiceless and voiced inter- dental fricatives [θ], [ð] and alveolar liquid [r] sounds among Chinese learners of English at University Utara ...
Mizanur Rahman, Dr. Md. Kamrul Hasan
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Assessing the Impact of Pronunciation Learning Strategy on Kurdish EFL Learners’ Pronunciation Accuracy

open access: yesمجلة جامعة كويه للعلوم الانسانية والاجتماعية, 2018
The study aimed at investigating the effectiveness of pronunciation learning strategies (in favor of Covert Rehearsal Model) in helping Kurdish EFL learners to acquire accuracy in English pronunciation and detecting the most frequently used strategy ...
Himdad A. Muhammad, Dlakhshan Y. Othman
doaj   +1 more source

Módní a nezbytné anglicismy ve vztahu k sociálním oblastem a k jejich výslovnosti a pravopisu [PDF]

open access: yesČasopis pro Moderní Filologii, 2019
This paper focuses on the distinction between luxury and necessary borrowings from English (i.e. Anglicisms) and the relationship between these borrowings, the domains in which they are used and their pronunciation and orthography.
Martin Havlík
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

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