Results 51 to 60 of about 1,488,747 (297)
Coal discard dump rehabilitation using kenaf: Proof of concept study [PDF]
MATEC Web of ConferencesCoal discards are a side effect from coal mining and beneficiation. There are currently billions of tons of discards, with South Africa reporting over 1000 Mt, mainly fine and ultra fine coals.
Boshoff Bianca +2 more
doaj +1 more source
A randomised controlled study of high intensity exercise as a dishabituating stimulus to improve hypoglycaemia awareness in people with type 1 diabetes:a proof of concept study [PDF]
, 2020 Aims/hypothesis Approximately 25% of people with type 1 diabetes have suppressed counterregulatory hormonal and symptomatic responses to insulin-induced hypoglycaemia, which renders them at increased risk of severe, disabling hypoglycaemia.
Farrell, Catriona M. +6 more
core +4 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
NP-guide: a portable projection-based navigation system for neurosurgery and beyond
Frontiers in NeurologyBackgroundStereotactic systems and various robot-assisted navigation platforms in neurosurgery have enabled high-precision localization. However, these systems, while highly accurate, are expensive, technically demanding, and procedurally complex, making
Zhongjie Shi +12 more
doaj +1 more source
Dose-response between frequency of breaks in sedentary time and glucose control in type 2 diabetes: a proof of concept study [PDF]
, 2019 Objectives This study aimed to investigate dose-response between frequency of breaks in sedentary time and glucose control.DesignRandomised three-treatment, two-period balanced incomplete block trial.MethodsTwelve adults with type 2 diabetes (age, 60 ...
Chastin, Sebastien F.M. +5 more
core +2 more sources
Ureteroscopy under conscious sedation: A proof-of-concept study
Canadian Urological Association Journal, 2022 Introduction: Ureteroscopies (URSs) are commonly performed under general anesthesia (GA) to maximize patient tolerability and minimize surgical complications. However, given the improvements in endoscopic technology and risks associated with GA, alternate forms of anesthesia have been postulated. We aimed to evaluate the outcomes of URS under conscious
Kunal, Jain +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Ward Identities and Renormalization of General Gauge Theories [PDF]
, 2001 We introduce the concept of general gauge theory which includes Yang-Mills models. In the framework of the causal approach and show that the anomalies can appear only in the vacuum sector of the identities obtained from the gauge invariance condition by ...
Grigore, Dan Radu
core +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source