Results 61 to 70 of about 1,488,747 (298)

Low-background temperature sensors fabricated on parylene substrates

, 2015
Temperature sensors fabricated from ultra-low radioactivity materials have been developed for low-background experiments searching for neutrinoless double-beta decay and the interactions of WIMP dark matter.
Barton, P. J., Dhar, A., Larsen, J. T., Loach, J. C., Poon, A. W. P.   +4 more
core   +1 more source

Using network analysis for the prediction of treatment dropout in patients with mood and anxiety disorders: a methodological proof-of-concept study [PDF]

, 2018
There are large health, societal, and economic costs associated with attrition from psychological services. The recently emerged, innovative statistical tool of complex network analysis was used in the present proof-of-concept study to improve the ...
Fisher, Aaron J., Hofmann, Stefan G., Husen, Kristin, Lutz, Wolfgang, Rubel, Julian A., Schwartz, Brian   +5 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Efficacy and safety of topical phenytoin cream in diabetic foot ulcers: A randomized, open-label, parallel, and proof-of-concept study

Perspectives in Clinical Research
Background: Diabetic foot ulcers (DFUs) are a severe diabetes complication, often leading to amputations. Despite medical advancements, no standard treatment exists. Conventional care is insufficient, prompting research into new therapies.
A. Vinayak, Sujeet K. Bhilwade, Aarsh P. Gajjar, Anjali S. Shah, Monty U. Khajanchi, Mahesh N. Belhekar, Ram P. Prajapati, Bhaskar Krishnamurthy   +7 more
doaj   +1 more source

Plasma lipoproteome in Alzheimer’s disease: a proof-of-concept study

Clinical Proteomics, 2018
Background Although total plasma lipoproteome consists of proteins that have shown promises as biomarkers that can identify Alzheimer’s disease (AD), effect sizes are modest.
Danni Li, Fangying Huang, Yingchun Zhao, Peter W. Villata, Timothy J. Griffin, Lin Zhang, Ling Li, Fang Yu   +7 more
doaj   +1 more source

Can verbal suggestions strengthen the effects of a relaxation intervention? [PDF]

, 2019
Short stress management interventions such as relaxation therapy have demonstrated preliminary effectiveness in reducing stress-related problems. A promising tool to strengthen the effectiveness of relaxation-based interventions is the use of verbal ...
Evers, Andrea W. M., Manai, Meriem, Meeuwis, Stefanie H., Schakel, Lemmy, Van Dessel, Pieter, van Middendorp, Henriet, Veldhuijzen, Dieuwke S.   +6 more
core   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Internet of Things Smart Sunscreen Station: Descriptive Proof-of-Concept Study

Journal of Medical Internet Research, 2020
BackgroundSkin cancer is the most prevalent but also most preventable cancer in Australia. Outdoor workers are at increased risk of developing skin cancer, and improvements in sun protection are needed.
Ford, Helen, Herbert, Jeremy, Horsham, Caitlin, Wall, Alexander, Hacker, Elke   +4 more
doaj   +1 more source

Constraining the geometry of AGN outflows with reflection spectroscopy [PDF]

, 2018
We collate active galactic nuclei (AGN) with reported detections of both relativistic reflection and ultra-fast outflows. By comparing the inclination of the inner disc from reflection with the line-of-sight velocity of the outflow, we show that it is ...
Buisson, D. J. K., Gallo, L. C., Jiang, J., Kara, E., Matzeu, G. A., Parker, M. L., Walton, D. J.   +6 more
core   +2 more sources