Results 41 to 50 of about 5,559 (204)

A Comprehensive Assessment of Renal Function During and After Pulsed Field Ablation

Journal of Cardiovascular Electrophysiology, Volume 37, Issue 6, Page 1259-1267, June 2026.
ABSTRACT Background Acute kidney injury is an uncommon complication of pulsed field ablation (PFA). There is, however, limited empirical data on the dynamics of renal biomarkers apart from creatinine. Furthermore, no study to date has assessed creatinine at more than 24 h after the procedure. Methods Patients undergoing PFA for atrial fibrillation (AF)
Václav Melenovský, Marek Hozman, Sabri Hassouna, Ivana Fišerová, Barbora Bačová, Dalibor Heřman, Jakub Karch, Jana Veselá, Michal Zuzčák, Ivan Rychlík, Pavel Osmančík   +10 more
wiley   +1 more source

Effects of propafenone on sinus node function in the rabbit heart

, 1990
Propafenone is a type 1C antiarrhythmic drug with efficacy for both ventricular and supraventricular arrhythmias. We investigated the effects of propafenone on properties of sinus node function in an in vitro preparation of rabbit sinus node and ...
Charles R. Kerr
core   +1 more source

Long‐Term Outcomes of Radiofrequency Atrioventricular Node Ablation in a Real‐World Population

Pacing and Clinical Electrophysiology, Volume 49, Issue 6, Page 698-706, June 2026.
ABSTRACT Background While interventional strategies have expanded the options for long term rhythm restoration, rate control continues to play a pivotal role in the treatment of atrial arrhythmias; however, pharmacologic strategies alone often fail in achieving effective rate control.
Vanessa Sciacca, Nora‐Kristin Brandt, Thomas Fink, Denise Guckel, Maximilian Mörsdorf, Yuri Bocchini, Martin Braun, Moneeb Khalaph, Karen Harutyunyan, Nadica Trajkovska, Philipp Lucas, Thomas Eitz, Maxim Didenko, Philipp Sommer, Christian Sohns   +14 more
wiley   +1 more source

Brugada-Phenocopy Induced by Propafenone Overdose and Successful Treatment: A Case Report

Balkan Medical Journal, 2017
Background: Brugada syndrome is an inherited arrhythmogenic disease that may cause sudden cardiac death due to ventricular fibrillation in young adults. Brugada syndrome caused by propafenone intoxication has been noted rarely in the literature.
Mehmet Emre Arı, Filiz Ekici
doaj   +1 more source

Efficacy and Safety of Catheter Ablation for Atrial Arrhythmias in Solid Organ Transplant Recipients: A Single‐Center Experience

Clinical Cardiology, Volume 49, Issue 5, May 2026.
Catheter ablation for complex atrial arrhythmias in solid organ transplant recipients is feasible using contemporary techniques, with arrhythmia‐free survival and periprocedural complication rates comparable to matched non‐transplant controls. ABSTRACT Introduction Atrial arrhythmias are common among solid organ transplant recipients and independently ...
Piotr Gardziejczyk, Martyna Skrzyńska‐Kowalczyk, Marta Skowrońska, Ewa Wlazłowska‐Struzik, Pawel Szymkiewicz, Piotr Pruszczyk, Jakub Baran   +6 more
wiley   +1 more source

Propafenone: A new agent for ventricular arrhythmia

, 1984
Propafenone, a new antiarrhythmic agent, was utilized in 30 patients with diverse heart disease who presented with sustained hemodynamically unstable ventricular arrhythmia.
Lown, Bernard, Podrid, Philip J.
core   +1 more source

Discovery of 4‐Quinazolinone‐Containing Phenylalanine Derivatives as Potent, Resistant‐Tolerant HIV Capsid Inhibitors

MedComm, Volume 7, Issue 5, May 2026.
Novel phenylalanine derivatives were identified as HIV‐1 capsid inhibitors. IC‐2i showed significant anti‐HIV‐1 activity at picomolar concentrations. ABSTRACT The HIV‐1 capsid (CA) is a validated antiviral target that plays critical roles in both the early and late stages of the viral life cycle.
Xujie Zhang, Lin Sun, Laura Walsham, Yuexi Ma, Dang Ding, Mei Wang, Fabao Zhao, Jian Zhang, Zhao Wang, Shujing Xu, Xiangyi Jiang, Yang Zhou, Erik De Clercq, Christophe Pannecouque, Chin‐Ho Chen, David C. Goldstone, Xinyong Liu, Alexej Dick, Peng Zhan   +18 more
wiley   +1 more source

Efficacy of propafenone in Wolff-Parkinson-White syndrome: Electrophysiologic findings and long-term follow-up

, 1987
The efficacy and safety of intravenous propafenone was studied in 10 patients with Wolff-Parkinson-White syndrome and in 2 patients with a concealed accessory pathway. During electrophysiologic study, the effect of propafenone on the effective refractory
Ludmer, Paul L., McGowan, Noreen E., Antman, Elliott M., Friedman, Peter L.   +3 more
core   +1 more source

Opening closed inward rectifier potassium channel doors

British Journal of Pharmacology, Volume 183, Issue 10, Page 2197-2218, May 2026.
Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non‐excitable tissues. Although KIR channels exhibit a biophysical preference for potassium influx due to voltage‐dependent block of outward current by polyamines and Mg2+, under physiological conditions, they predominantly mediate K+ efflux ...
Anna Stary‐Weinzinger, Fabian Kaiser, Marcel A. G. van der Heyden, Saïd Bendahhou   +3 more
wiley   +1 more source

Successful Treatment of Propafenone Intoxication With Intravenous Lipid Emulsion

, 2015
Severe cardiac effects, including cardiac arrest, are a rare complication of high-dose propafenone intake. Among patients who experience cardiac arrest, the survival rate is low.
Kose, Isil, BAYRAM, BAŞAK, Acara, Cagdas, Arslan, Abdulla, Avci, Sinem   +4 more
core   +1 more source