Results 31 to 40 of about 4,499 (142)
The Journal of Physiology, EarlyView.Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato +3 more
wiley +1 more source
Opening closed inward rectifier potassium channel doors
British Journal of Pharmacology, Volume 183, Issue 10, Page 2197-2218, May 2026.Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non‐excitable tissues. Although KIR channels exhibit a biophysical preference for potassium influx due to voltage‐dependent block of outward current by polyamines and Mg2+, under physiological conditions, they predominantly mediate K+ efflux ...
Anna Stary‐Weinzinger +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1177-1185, April 2026.Aim Our international cohort study assessed the comparative effectiveness and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) among patients with non‐valvular atrial fibrillation (NVAF) using antiarrhythmic drugs. Methods Using the United Kingdom's (UK's) Clinical Practice Research Datalink Aurum and Québec claims data, we
Fabian Maximilian Meinert +5 more
wiley +1 more source
Clinical Cardiology, Volume 49, Issue 4, April 2026.This study demonstrates that combined RFCA and right atrial Ao‐SVC GP ablation provides a one‐stop, innovative solution for patients with vagal bradycardia and concomitant tachyarrhythmias, significantly improving symptoms and reducing syncope. ABSTRACT Background Frequent premature ventricular contractions (PVCs) or paroxysmal supraventricular ...
Xinai Meng +6 more
wiley +1 more source
Brugada-Phenocopy Induced by Propafenone Overdose and Successful Treatment: A Case Report
Balkan Medical Journal, 2017 Background: Brugada syndrome is an inherited arrhythmogenic disease that may cause sudden cardiac death due to ventricular fibrillation in young adults. Brugada syndrome caused by propafenone intoxication has been noted rarely in the literature.
Mehmet Emre Arı, Filiz Ekici
doaj +1 more source
Kuwait Atrial Fibrillation Management Analysis—Insights From a Tertiary Center in Kuwait
Journal of Arrhythmia, Volume 42, Issue 2, April 2026.Among patients with non‐valvular AF, rhythm control (RC) was pursued in 28.9%. RC was pursued for younger patients and those followed in electrophysiology clinics (33% vs. 5%, p < 0.001). 11.6% of patients received an underdosed DOAC. RC was underutilized in our study, falling short of international benchmarks and guideline recommendations.
S. AlKharji +3 more
wiley +1 more source
The Evolving Role of Ivabradine for Focal Atrial Tachycardia: A Systematic Review
Journal of Arrhythmia, Volume 42, Issue 2, April 2026.Overview of the evolving role of ivabradine in focal atrial tachycardia (FAT), highlighting its HCN‐mediated mechanism, features of ivabradine‐sensitive FAT, hypothesized predictors of response, special populations requiring special considerations, and potential adverse effects.
Haikal Balweel +5 more
wiley +1 more source
European Journal of Clinical Investigation, Volume 56, Issue 4, April 2026.In this large European–Asian cohort of patients with atrial fibrillation, liver disease was linked to lower oral anticoagulant use—particularly in Europe—and to higher risks of mortality and cardiovascular events. These findings highlight the adverse impact of liver disease, especially when oral anticoagulation is withheld.
Davide Antonio Mei +9 more
wiley +1 more source
Propafenone and amiodarone efficacy in paroxysmal atrial fibrillation treatment
Российский кардиологический журнал, 2006 To assess antiarrhythmic efficacy of propafenone and amiodarone in paroxysmal atrial fibrillation (AF) treatment, 204 patients (125 males, 79 females, aged 57-72 years) with various stages of heart failure (HF) were examined.
N. N. Isakova +5 more
doaj
Clinical Cardiology, Volume 49, Issue 3, March 2026.In Asian patients with hypertrophic cardiomyopathy, integrating NT‐proBNP with the clinical HCM‐AF score provides significant incremental prognostic value. This combined multiparametric assessment enhances the predictive accuracy for new‐onset atrial fibrillation, enabling more precise risk stratification and targeted clinical management.
Yi‐Peng Gao +10 more
wiley +1 more source