Temporal Characteristics and Management of Prolonged Sinus Pause Following Atrial Fibrillation Termination After Catheter Ablation-A Preliminary Study. [PDF]
Ann Noninvasive ElectrocardiolTwelve of the 1330 patients who underwent AF catheter ablation showed PSP ≥ 3 s after AF termination post ablation. The temporal characteristics of PSP were described. Nine of the 12 patients had no need for permanent pacing. We concluded that a ‘watch‐and‐wait’ strategy could be adopted in these patients.
Guo Y +12 more
europepmc +2 more sources
Beyond the Michaelis-Menten: Evaluation of a tQSSA-Based IVIVE Approach for Predicting In Vivo Intrinsic Clearance From Hepatocyte Assays. [PDF]
CPT Pharmacometrics Syst PharmacolABSTRACT The classical Michaelis–Menten model, under the standard quasi‐steady‐state approximation (sQSSA), is widely used in in vitro‐in vivo extrapolation (IVIVE) studies using hepatocyte or human liver microsomal (HLM) assays to predict intrinsic hepatic clearance (Clint,vitro$$ {\mathrm{Cl}}_{\operatorname{int},\mathrm{vitro}} $$).
Vu NT +6 more
europepmc +2 more sources
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Testing of newly synthesized propafenone derivatives antiarrhythmic activity in aconitic model of cardiac arrhythmia in rats [PDF]
Veterinarski Glasnik, 2014 By applying of aconitic test in in vivo experiments in rats under deep anesthesia, there was investigated the antiarrhythmic potential of newly synthetized fluorinated derivatives of propafenone.
Ivković Branka +6 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2021 Objective: To determine using a systematic assessment and meta-analysis if GFA injection is an appropriate substitute of propafenone for arrhythmic.Design: Conduct a systematic review and meta-analysis of randomized controlled trials.Data Source: PubMed,
Jinming Song +5 more
doaj +1 more source
Predictors of class IC antiarrhythmic drugs efficacy in patients with paroxysmal form of atrial fibrillation [PDF]
Consilium Medicum, 2023 Background. Class IC antiarrhythmic drugs (IC-AADs) are recommended as first-line therapy in treatment of lone paroxysmal atrial fibrillation (AF) along with catheter ablation of pulmonary veins.
Manizha A. Khalikova +3 more
doaj +1 more source
Frontiers in Pediatrics, 2020 Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare cardiac disease in children, and can lead to sudden cardiac death (SCD). Propafenone is classIC antiarrhythmic medication, and its side effects include cardiovascular compromise in the form
Yan-qiu Chu +3 more
doaj +1 more source
Pharmacokinetics of propafenone hydrochloride sustained-release capsules in male beagle dogs
Acta Pharmaceutica Sinica B, 2015 This paper describes the development and validation of a liquid chromatography–mass spectrometric assay for propafenone and its application to a pharmacokinetic study of propafenone administered as a new propafenone hydrochloride sustained-release ...
Liping Pan +6 more
doaj +1 more source
Frontiers in Physiology, 2019 Background: “Pill-in-the-pocket” (PIP) treatment with type IC drugs for cardioversion of recent-onset atrial fibrillation (AF) has been recommended in guidelines.
Linling Li +10 more
doaj +1 more source
Suicide attempt of young woman by Propafenone overdose - case report
Journal of Education, Health and Sport, 2023 Introduction and purpose: Over the last few years, the number of suicide attempts in Polish women has been steadily increasing. This report presents a case of a 18 years old woman hospitalized in the Toxicology and Cardiology Department due to poisoning
Marcin Wais +2 more
doaj +1 more source