Results 81 to 90 of about 5,559 (204)

Efficacy and safety of 1C class antiarrhythmic agent (propafenone) for supraventricular arrhythmias in septic shock compared to amiodarone: protocol of a prospective randomised double-blind study

BMJ Open, 2019
Introduction Supraventricular arrhythmias contribute to haemodynamic compromise in septic shock. A retrospective study generated the hypothesis that propafenone could be more effective than amiodarone in achieving and maintaining sinus rhythm (SR ...
Martin Balik, Petr Waldauf, Michal Maly, Vojtech Matousek, Tomas Brozek, Jan Rulisek, Michal Porizka, Robert Sachl, Michal Otahal, Petr Brestovansky, Eva Svobodova, Marek Flaksa, Zdenek Stach, Jaroslav Pazout, Frantisek Duska, Ondrej Smid, Martin Stritesky   +16 more
doaj   +1 more source

Atrial fibrillation: Adverse effects of "pill-in-the-pocket" treatment and propafenone-carvedilol interaction.

, 2010
Propafenone and carvedilol share a common hepatic metabolism involving the oxidative pathway (CYP2D6). Therefore, oral loading with propafenone (as "pill-in-the-pocket" treatment of recent-onset atrial fibrillation) in a patient on concurrent carvedilol ...
Domenichini G, BORIANI, Giuseppe, Biffi M, Martignani C., Marziali A, Diemberger I   +5 more
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Efeitos da associação propafenona - propofol na contratilidade miocárdica, freqüência cardíaca, fluxo coronariano e incidência de arritmia em corações isolados de ratos Effects of propafenone associated with propofol on myocardial contractility, heart rate, coronary flow, and the incidence of arrhythmia in isolated hearts of rats

Arquivos Brasileiros de Cardiologia, 2004
OBJETIVO: Estudar a influência da propafenona associada ao propofol na contratilidade miocárdica (dP/dt e freqüência cardíaca), fluxo coronariano e incidência de arritmia em corações isolados de ratos.
Nilcéa Leal de Moraes Assis, Otoni Moreira Gomes, Silvério Leonardo Macedo Garcia, Guilherme Gustavo do Valle   +3 more
doaj   +1 more source

Double-blind study of intravenous propafenone for paroxysmal supraventricular reentrant tachycardia

, 1987
Propafenone was administered during electrophysiologic testing to determine its efficacy and safety for terminating and preventing reinduction of paroxysmal supraventricular reentrant tachycardia. Four men and 10 women (mean age 50 years, range 28 to 69)
McLaran, Christopher J., Holmes, David R., Osborn, Michael J., Hammill, Stephen C., Gersh, Bernard J., Wood, Douglas L.   +5 more
core   +1 more source

Long-term oral propafenone therapy for suppression of refractory symptomatic atrial fibrillation and atrial flutter

, 1988
Sixty patients who had recurrent episodes of symptomatic atrial fibrillation or flutter, or both, and who had failed one to five prior drug trials were treated with open label oral propafenone hydrochloride.
McGowan, Noreen, Antman, Elliott M., Goldman, Lee, Cantillon, Catherine, Friedman, Peter L., Beamer, Andrew D.   +5 more
core   +1 more source

Antiarrhythmic therapy choice in patients with left ventricular diastolic dysfunction and atrial fibrillation

Кардиоваскулярная терапия и профилактика, 1970
Aim. To study clinical effectiveness, safety, and effects on left ventricular (LV) systolic and diastolic function for Class IC and Class III antiarrhythmic medications — propafenone and amiodarone, respectively — in patients with chronic heart failure ...
A. V. Tarasov, O. N. Miller, Yu. M. Pozdnyakov, S. A. Luchinskyi, V. L. Doshchitsyn   +4 more
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Ventricular Tachycardia Induced by Propafenone Intoxication in a Pediatric Patient

, 2019
Unintentional poisonings are a global health problem frequently resulting in hospital admissions. Propafenone is a class 1C antiarrhythmic drug used in the second-line management of supraventricular and ventricular arrhythmias and, when unintentionally ...
Marzuillo P., Tipo V., Pappacoda S., D'Anna C., Ponticiello E., Rosa M., Di Mita O.   +6 more
core   +1 more source

Propafenone for the prevention of atrial tachyarrhythmias after cardiac surgery: a randomized, double-blind placebo-controlled trial

, 2008
We studied the efficacy of propafenone in preventing atrial tachyarrhythmias after cardiac surgery, and the possible relationships between CYP2D6 polymorphism and the efficacy, pharmacokinetics, and tolerability of propafenone.
Kivisto, K., Hofmann, U., Jagle, C., Igel, S., Wagner, F., Meisner, C., Delabar, U., Bohm, J., Ziemer, G., Schaeffeler, E., Engel, C., Hellberg, K., Drescher, S., Fux, R., Rein, J., Marx, C., Eichelbaum, M., Morike, K., Gleiter, C., Bail, D., et al.   +20 more
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Propafenone overdose: Cardiac arrest and full recovery

, 2010
Intoxication caused by propafenone is very rare, and there are no known detailed epidemiological studies. We present the clinical manifestation of severe propafenone intoxication,successfully treated in a 17 year-old male. He was brought to the Intensive
Wożakowska-Kapłon, Beata; 1st Clinical Department of Cardiology, Swietokrzyskie Centre of Cardiology, Kielce, Poland, Stępień-Walek, Alicja   +1 more
core  

Antiarrhythmic therapy effects on quality of life among patients with extrasystoles

Российский кардиологический журнал, 2008
To investigate antiarrhythmic therapy effectiveness, safety and impact on quality of life (QoL) among patients with symptomatic extrasystolia, a study was performed in 152 individuals, with 140 completing the study. Mean age of the patients was 57 years;
V. L. Doshchitsyn, O. A. Kramynina, E. V. Chernova, O. B. Karpunichev, O. V. Barysheva, E. Yu. Shatykhina, Yu. V. Bezborodova   +6 more
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