Results 81 to 90 of about 5,973 (205)

Propafenone-Induced Cholestatic Liver Injury: When Diagnosis Does Not Skip a Beat

open access: yesGE: Portuguese Journal of Gastroenterology
Introduction: Propafenone is a widely used class Ic antiarrhythmic drug that is mainly metabolised by the liver. Hepatotoxicity associated with propafenone is rare, with only a few clinical cases reported in the literature.
Ana Isabel Ferreira   +5 more
doaj   +1 more source

Electrophysiologic effects and clinical efficacy of oral propafenone therapy in patients with ventricular tachycardia [PDF]

open access: yes, 1985
The effects of the antiarrhythmic agent propafenone were evaluated in 25 patients with recurrent symptomatic ventricular tachycardia. Oral propafenone was given to a maximal dose of 300 mg every 8 hours.
Chilson, Donald A.   +4 more
core   +1 more source

A case of lethal suicidal intoxication with propafenone and diazepam

open access: yesAnnals of Noninvasive Electrocardiology
Diazepam poisoning is a common emergency situation, but propafenone poisoning is relatively rare. We reported a case of propafenone poisoning combined with diazepam.
Shuangbing Yan   +4 more
doaj   +1 more source

Atrial fibrillation: Adverse effects of "pill-in-the-pocket" treatment and propafenone-carvedilol interaction.

open access: yes, 2010
Propafenone and carvedilol share a common hepatic metabolism involving the oxidative pathway (CYP2D6). Therefore, oral loading with propafenone (as "pill-in-the-pocket" treatment of recent-onset atrial fibrillation) in a patient on concurrent carvedilol ...
Domenichini G   +5 more
core   +1 more source

Chronic Propafenone Application Increases Functional K IR2.1 Expression In Vitro. [PDF]

open access: yes, 2023
Expression and activity of inwardly rectifying potassium (K IR) channels within the heart are strictly regulated. K IR channels have an important role in shaping cardiac action potentials, having a limited conductance at depolarized potentials but ...
Woolschot, Liset   +3 more
core  

Successful Treatment of Suicide Attempt by Megadose of Propafenone and Captopril

open access: yes, 2013
Intoxication caused by propafenone is very rare, and there is no case reported before propafenone and captopril intoxication together. There are few case reports in the literature about intoxication with more than 6 g of propafenone.
Avci, Ahmet   +4 more
core   +1 more source

Propafenone efficacy in treatment of atrial fibrillation paroxysms: a placebo-controlled study

open access: yesРоссийский кардиологический журнал, 2005
In a placebo-controlled study, propafenone efficacy and safety for pharmaceutical cardioversion in atrial fibrillation (AF) paroxysms were studied. The study included 50 patients aged 28-69 years (mean age 53,9+9,7), with AF paroxysms lasting for less ...
Yu. A. Bunin, L. K. Anfalova
doaj  

Efficacy and safety of 1C class antiarrhythmic agent (propafenone) for supraventricular arrhythmias in septic shock compared to amiodarone: protocol of a prospective randomised double-blind study

open access: yesBMJ Open, 2019
Introduction Supraventricular arrhythmias contribute to haemodynamic compromise in septic shock. A retrospective study generated the hypothesis that propafenone could be more effective than amiodarone in achieving and maintaining sinus rhythm (SR ...
Martin Balik   +16 more
doaj   +1 more source

Antiarrhythmic therapy choice in patients with left ventricular diastolic dysfunction and atrial fibrillation

open access: yesКардиоваскулярная терапия и профилактика, 1970
Aim. To study clinical effectiveness, safety, and effects on left ventricular (LV) systolic and diastolic function for Class IC and Class III antiarrhythmic medications — propafenone and amiodarone, respectively — in patients with chronic heart failure ...
A. V. Tarasov   +4 more
doaj  

Efeitos da associação propafenona - propofol na contratilidade miocárdica, freqüência cardíaca, fluxo coronariano e incidência de arritmia em corações isolados de ratos Effects of propafenone associated with propofol on myocardial contractility, heart rate, coronary flow, and the incidence of arrhythmia in isolated hearts of rats

open access: yesArquivos Brasileiros de Cardiologia, 2004
OBJETIVO: Estudar a influência da propafenona associada ao propofol na contratilidade miocárdica (dP/dt e freqüência cardíaca), fluxo coronariano e incidência de arritmia em corações isolados de ratos.
Nilcéa Leal de Moraes Assis   +3 more
doaj   +1 more source

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