Results 41 to 50 of about 1,668 (193)

Different Strategies of Asymmetric Synthesis [PDF]

Asymmetric synthesis is one of the significant subjects of research in recent times. It incorporates regulating stereochemistry of compounds to produce enantiomerically pure chemical substances. Chiral auxiliaries/substrates and enantioselective reagents
Hemant Khambete, Khushboo Arora, Ritu Sapra, Sanjay Jain, Sumeet Prachand   +4 more
core   +3 more sources

Some distorted thoughts about ketamine as a psychedelic and a novel hypothesis based on NMDA receptor-mediated synaptic plasticity. [PDF]

, 2018
Ketamine, a channel blocking NMDA receptor antagonist, is used off-label for its psychedelic effects, which may arise from a combination of several inter-related actions.
Bortolotto, ZA, Collingridge, GL, Ingram, R, Jane, DE, Kang, H, Lightman, S, Lodge, D, Volianskis, A   +7 more
core   +3 more sources

Nickel‐Catalyzed O‐Arylation of N‐Protected Amino Alcohols with (Hetero)aryl Chlorides

Chemistry – A European Journal, Volume 31, Issue 10, February 17, 2025.
The first effective base metal‐catalyzed protocol for C−O cross‐coupling of primary, secondary, and tertiary alcohol‐containing N‐Boc protected amino alcohols with (hetero)aryl chlorides, affording access to new and useful N‐protected aryloxyamine compounds, is reported.
Kathleen M. Morrison, Emily C. Jackson, Erika M. H. Elliott, Mark Stradiotto   +3 more
wiley   +1 more source

Synthesis and biological evaluation of thiazolidinedione derivatives of chalcones and flavones as antihyperglycemic and antidyslipidemic agents  [PDF]

, 2021
A series of chalcone and flavone derivatives (6a-d, 9a-f) based on 2,4-thiazolidinedione have been synthesized and evaluated for in vivo antihyperglycemic activity in sucrose loaded (SLM) and streptozotocin (STZ) induced diabetic animal models and also ...
Pratap, Ram , Satyanarayana, Mavurapu , Shukla, Poonam , Srivastava, Arvind K, Tiwari, Priti , Tripathi, Brajendra K   +5 more
core   +4 more sources

Characterization of a solvent for chemical absorption-based CO2 capture [PDF]

, 2021
The diploma thesis is focused on the thermodynamic characterization of an aqueous 3-amino-1-propanol (AP) solution, which is used as a promising solvent for post-combustion CO2 capture from exhaust gases.
Bunevska, Tanja
core  

Straightforward Synthesis of 1‐aryloxy‐1,1‐difluoro‐3‐aminopropan‐2‐ols – Accessing Fluorinated Derivatives of Commercialized Beta‐Blockers

European Journal of Organic Chemistry, Volume 27, Issue 35, September 16, 2024.
An array of 1‐aryloxy‐1,1‐difluoro‐3‐aminopropan‐2‐ols were synthesized using iodohydroxylation of gem‐difluorinated allyl aryl ethers followed by epoxidation and ring‐opening with an amine in a one‐pot/two‐step fashion. This approach allows the synthesis of a set of gem‐difluorinated derivatives of commercialized beta‐blockers.
Jan‐Ole Moritz, Shuang Liu, Katharina Konieczny, Dirk Michalik, Udo Kragl, Helfried Neumann, Matthias Beller   +6 more
wiley   +1 more source

Crystal structures, electron spin resonance, and thermogravimetric analysis of three mixed‐valence copper cyanide polymers

Acta Crystallographica Section C, Volume 80, Issue 6, Page 212-220, June 2024.
The crystal structures of three mixed‐valence copper cyanide polymers with similar polymeric CuCN networks are described, together with the results of electron spin resonance and thermogravimetric analyses.The crystal structures of three mixed‐valence copper cyanide alkanolamine polymers are presented, together with thermogravimetric analysis (TGA) and
Peter W. R. Corfield, Ahmed Elsayed, Tristan DaCunha, Christopher Bender   +3 more
wiley   +1 more source

Effects of congeners of amphetamine on the human heart [PDF]

Central stimulatory and hallucinogenic drugs of abuse like amphetamine and most congeners of amphetamine can have cardiac harmful effects. These cardiac side effects can lead to morbidities and death.
Dhein, Stefan, Gergs, Ulrich, Hofmann, Britt, Kirchhefer, Uwe, Neumann, Joachim   +4 more
core   +1 more source

Evaluation of fresh state, rheological properties, and compressive strength performance of cementitious system with grinding aids

Journal of Applied Polymer Science, Volume 141, Issue 15, April 15, 2024.
Synergic Interaction of Amine Based GAs with PCE cement systems. Abstract Grinding aids (GA) affect the fresh and hardened state properties of cement systems in addition to the economic and ecological advantages they provide. Nevertheless, there is not enough information in the literature regarding the effect of GA utilization on the rheological ...
Yahya Kaya, Veysel Kobya, Ali Mardani
wiley   +1 more source

Enantioselective Synthesis of Antiepileptic Drug: (-)-Levetiracetam—Synthetic Applications of the Versatile New Chiral N [PDF]

, 2013
We report an asymmetric synthesis of (-)-Levetiracetam (1) in six steps starting from versatile new chiral N-sulfinimine (3). The key step, stereoselective 1,2-addition of ethylmagnesium bromide (EtMgBr) to chiral N-sulfinimine derived from (R ...
E. Naresh, G. Madhusudhan, K. Chandra Babu, K. Mukkanti, K. Ram Mohan, R. Buchi Reddy   +5 more
core   +1 more source