Non-Systemic Drugs: A Critical Review [PDF]
, 2012 Non-systemic drugs act within the intestinal lumen without reaching the systemic circulation. The first generation included polymeric resins that sequester phosphate ions, potassium ions, or bile acids for the treatment of electrolyte imbalances or ...
Charmot, Dominique
core +3 more sources
Eugenol ve timol içeren yeni oksipropanolamin türevlerinin sentezi ve antibakteriyel özelliklerinin araştırılması [PDF]
, 2019 06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması ...
Kestane, Ali
core
Oxa-Michael Addition to alpha,beta-Unsaturated Nitriles:An Expedient Route to gamma-Amino Alcohols and Derivatives [PDF]
, 2018 Water addition to alpha,beta-unsaturated nitriles would give facile access to the -hydroxy-nitriles, which in turn can be hydrogenated to the gamma-amino alcohols.
de Vries, Johannes G. +3 more
core +1 more source
Best Available Techniques (BAT) Reference Document for the Production of Large Volume Organic Chemicals. Industrial Emissions Directive 2010/75/EU (Integrated Pollution Prevention and Control) [PDF]
, 2017 The Best Available Techniques (BAT) Reference Document (BREF) for the Production of Large Volume Organic Chemicals is part of series of documents presenting the results of an exchange of information between EU Member States, the industries concerned, non-
BRINKMANN THOMAS +9 more
core +2 more sources
Butylglyceryl pectin nanoparticles: synthesis, formulation and characterization [PDF]
, 2019 Pectin is a polysaccharide with very good gel forming properties that traditionally has found important applications in foods and pharmaceutical industries.
Arafat, Mosab +4 more
core +1 more source
Enantioselective Synthesis of Antiepileptic Drug: (-)-Levetiracetam-Synthetic Applications of the Versatile New Chiral N-Sul�nimine [PDF]
, 2020 We report an asymmetric synthesis of (-)-Levetiracetam (1) in six steps starting from versatile new chiral N-sul nimine (3). e key step, stereoselective 1,2-addition of ethylmagnesium bromide (EtMgBr) to chiral N-sul nimine derived from (R ...
E Naresh +5 more
core
Characterization of BU09059:A novel potent selective κ-receptor antagonist [PDF]
, 2014 [Image: see text] Kappa-opioid receptor (κ) antagonists are potential therapeutic agents for a range of psychiatric disorders. The feasibility of developing κ-antagonists has been limited by the pharmacodynamic properties of prototypic κ-selective ...
Bailey, Sarah J +7 more
core +1 more source
High Regio- and Stereoselective Multi-enzymatic Synthesis of All Phenylpropanolamine Stereoisomers from β-Methylstyrene [PDF]
, 2021 Corrado, M.L., Knaus, T., Mutti, F.G.
core +3 more sources
Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors [PDF]
, 2019 Context-dependent inhibition of N-methyl-D-aspartate (NMDA) receptors has important therapeutic implications for the treatment of neurological diseases that are associated with altered neuronal firing and signaling.
Furukawa, H. +8 more
core +1 more source