Results 51 to 60 of about 16,925,620 (257)
Advanced Modeling and Simulation in Engineering SciencesMultiple model reduction techniques have been proposed to tackle linear and non-linear problems. Intrusive model order reduction techniques exhibit high accuracy levels; however, they are rarely used as a standalone industrial tool because of the high ...
Mikhael Tannous +4 more
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Thermo-Hydraulic Modelling and Experimental Validation of an Electro-Hydraulic Compact Drive
Energies, 2021 Electro-hydraulic compact drives (ECDs) are an emerging technology for linear actuation in a wide range of applications. Especially within the low power range of 5–10 kW, the plug-and-play capability, good energy efficiency and small space requirements ...
Søren Ketelsen +5 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
An Integrated Business Model Based on Linear Programming for Carrageenan Production Chain in Coastal Village [PDF]
BIO Web of ConferencesThe blue economy concept is a development program that harmonizes economic growth, social equity, and a sustainable environment. In coastal villages, economic growth could be promoted by selecting a high-value and competitive local-based product ...
Widjaja Sjarief +4 more
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Applied Sciences, 2020 The transient proper orthogonal decomposition (TPOD) method is applied for order reduction in the rotor-bearing system with the coupling faults in this paper.
Kuan Lu +6 more
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Definition of a linear equivalent model for a non-linear system with impacts [PDF]
, 2012 Modal characteristics of non-linear system are typically studied through response to harmonic excitation and using various definitions of non-linear modes. However, few results are available for systems under broadband excitation.
BALMES, Etienne +2 more
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Adsorption Science & Technology, 2013 A very common practice during the parameter estimation of adsorption isotherms, including the well-known Langmuir and Freundlich isotherms, consists in manipulating the isotherm equation to obtain a linear equation and estimate the model parameters using
Taynara Andrea Osmari +5 more
doaj +1 more source