Results 31 to 40 of about 219,230 (257)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Gender neutral proper names: current situation and perspectives

open access: yesGender a Výzkum, 2023
Personal proper names are part of a community's language inventory. To a large extent, they verbalise gender stereotypes, expectations and norms, power relations,  political circumstances, and how minorities are treated. In my paper I analyse the current
Jana Valdrová
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Semantics of Agionym Nikolay (based on Russian Paroemia and Orthodox Prayers)

open access: yesВестник Волгоградского государственного университета: Серия 2. Языкознание, 2017
The article views proper name as a functional-semantical element of language, speech and culture. The relevance of the article is based on studying a proper name, name of the saint, as a component of the Russian language worldview and as a cultural ...
Margarita I. Kuzmina
doaj   +1 more source

Eventonym: A Specific Type of Advertising Proper Name

open access: yesВопросы ономастики, 2020
The paper uses a structural-semiotic approach to analyse the advertising names of special events (festivals, marathons, competitions, exhibitions, fairs, and other campaigns and projects for mass appeal) held mainly in the Samara region.
Tatyana P. Romanova
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

De la « transsubstantiation » discursive dans la traduction des textes médicaux

open access: yesStudia Romanica Posnaniensia, 2018
Every specialist text carries traces of the institutionalized context in which it is created. The context is based on the socially sanctioned communicative relationship, on the strength of which discourse partners enter into a so-called ...
Barbara Walkiewicz
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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