Results 51 to 60 of about 2,388,514 (295)

Proper Name as a Marker of a Cosmogonic Song [PDF]

open access: yesВопросы ономастики, 2017
The purpose of this article is to show the internal integrity of the Eddic Grímnismál (Sayings of Grímnir), putting forward that the proper name is the key element for understanding the structure and meaning of this Eddic song.
Tatiana V. Toporova
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Proper name in a normative scientific text

open access: yesНеофилология
INTRODUCTION. The ability of a proper name to reflect both subject information and multifaceted background information puts it on a par with the main carrier of scientific knowledge – a term.
N. A. Maksimchuk
doaj   +1 more source

On the Associative Potential of the Main Character’s Name in Tatyana Tolstaya’s Hunting the Wooly Mammoth [PDF]

open access: yesВопросы ономастики, 2013
The article focuses on the poetonym Zoya (Зоя) in Tatyana Tolstaya’s short story Hunting the Wooly Mammoth. The author analyzes the associative connections of the name in question and its influence on the formation of the character’s image, and reveals ...
Kseniya I. Baranova
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

A strictly Millian approach to the definition of the proper name

open access: yes, 2009
A strictly Millian approach to proper names is defended, i.e. one in which expressions when used properly ('onymically') refer directly, i.e. without the semantic intermediaryship of the words that appear to comprise them.
Coates, Richard   +1 more
core   +1 more source

Home - About - Disclaimer - Privacy