Results 51 to 60 of about 219,230 (257)

On the Associative Potential of the Main Character’s Name in Tatyana Tolstaya’s Hunting the Wooly Mammoth [PDF]

Вопросы ономастики, 2013
The article focuses on the poetonym Zoya (Зоя) in Tatyana Tolstaya’s short story Hunting the Wooly Mammoth. The author analyzes the associative connections of the name in question and its influence on the formation of the character’s image, and reveals ...
Kseniya I. Baranova
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Proper name in a normative scientific text

Неофилология
INTRODUCTION. The ability of a proper name to reflect both subject information and multifaceted background information puts it on a par with the main carrier of scientific knowledge – a term.
N. A. Maksimchuk
doaj   +1 more source

LINGUISTIC AND PRAGMATIC POTENTIAL OF ADVERTISING NAMES (AS EXEMPLIFIED BY NAMES OF COSMETIC GOODS)

Вестник Волгоградского государственного университета: Серия 2. Языкознание, 2020
The article focuses on specifics of advertising names given to cosmetic products. The purpose of work is to study the efficiency of the considered linguistic units influence on the addressee’s perception, and to analyze the information value of these ...
Marina Yu. Krinitskaya
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

An Algorithm for Variable-Length Proper-Name Compression

Information Technology and Libraries, 1970
Viable on-line search systems require reasonable capabilities to automatically detect (and hopefully correct) variations between request format and stored format.
James L. Dolby
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Imię Cyryl w antroponimii historycznej Brańska i okolic

Zeszyty Cyrylo-Metodiańskie, 2018
The Proper Name Cyril in the Historical Anthroponymy of Bransk and Its Surrounding Area. The paper offers an attempt to answer the question of the presence of onymic structures containing the proper name Cyril in the local historical anthroponymic ...
Złotkowski, Piotr
doaj   +1 more source