Results 71 to 80 of about 2,187,591 (335)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Nickname as Special Type of Onym: in Search of Integrated Sign
Известия Южного федерального университета: Филологические науки, 2018 Nicknames (network names) form special onomastic system which on the level of community and differentiation is comparable to the system of traditional personal names, but possesses a special arsenal of pragmatical, formal, grammatical, semantic and ...
Anastasia V. Zubareva
doaj +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Weighted Distributions: A Brief Review, Perspective and Characterizations [PDF]
, 2017 The weighted distributions are widely used in many fields such as medicine, ecology and reliability, to name a few, for the development of proper statistical models.
Hamedani, Gholamhossein G. +3 more
core +1 more source
A név szerepe Salman Rushdie "Hárún és a Mesék Tengere" című művében [PDF]
, 2011 The function of names in Salman Rushdie’s ‘Haroun and the Sea of Stories’ The paper examines how the proper names appearing in Salman Rushdie’s ‘Haroun and the Sea of Stories’ contribute to the interpretation of the work.
Slíz, Mariann
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Sociologies, 2020 The anthropomorphic projections aroused by humanoid robots tend to mobilize the grammar of distance or proximity, inclusion and exclusion, which is an eminently moral grammar.
Laurence Kaufmann, Olivier Glassey
doaj