Results 51 to 60 of about 108,088 (254)
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
A tulajdonnevek fordíthatóságáról és napjaink fordítási hibáiról, közszók és tulajdonnevek példáján
Névtani Értesítő, 2007 On the translation of proper names and on today’s mistranslations, considering proper names as well as common nouns The author concerns a set of problems shared by different branches of linguistics: translation, language education and onomastics. By
Tamás Farkas
doaj +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Proper Names as Rigid Designators
RUDN Journal of Philosophy, 2016 The article focuses on the critical analysis of the concept of proper names as rigid designators. The arguments in favor of the theory of meaning for ordinary proper names and its problems are considered.
A Z Chernyak
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YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Precedent Proper Names in Informal Oikonymy [PDF]
Вопросы ономастики, 2013 The paper deals with the Russian language informal city names (oikonyms) motivated by other toponyms (with reference to Russia and the CIS). The author shows that the motivating proper name can replace the city name (e. g.
Maria V. Akhmetova
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FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Frege: The Theory of Meaning Concerning Proper Names [PDF]
Kritike: An Online Journal of Philosophy, 2010 Gottlob Frege may be considered as the first intellectual giant in thePhilosophy of Language. He was the first to raise the issue ofmeaning by formulating an organized theory of meaning for a part ofnatural language as the theory of meaning is at the ...
Sikander Jamil
doaj