Results 51 to 60 of about 110,033 (259)

A tulajdonnevek fordíthatóságáról és napjaink fordítási hibáiról, közszók és tulajdonnevek példáján

open access: yesNévtani Értesítő, 2007
On the translation of proper names and on today’s mistranslations, considering proper names as well as common nouns The author concerns a set of problems shared by different branches of linguistics: translation, language education and onomastics. By
Tamás Farkas
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Precedent Proper Names in Informal Oikonymy [PDF]

open access: yesВопросы ономастики, 2013
The paper deals with the Russian language informal city names (oikonyms) motivated by other toponyms (with reference to Russia and the CIS). The author shows that the motivating proper name can replace the city name (e. g.
Maria V. Akhmetova
doaj  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

On the Literal Meaning of Proper Names

open access: yesAnálisis Filosófico, 2019
One of the main arguments in favor of metalinguistic predicativism is the uniformity argument. The article discusses one of its premises, according to which the Being Called Condition gives the literal meaning of proper names.
Nicolás Lo Guercio
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Frege: The Theory of Meaning Concerning Proper Names [PDF]

open access: yesKritike: An Online Journal of Philosophy, 2010
Gottlob Frege may be considered as the first intellectual giant in thePhilosophy of Language. He was the first to raise the issue ofmeaning by formulating an organized theory of meaning for a part ofnatural language as the theory of meaning is at the ...
Sikander Jamil
doaj  

Home - About - Disclaimer - Privacy