Results 61 to 70 of about 2,073,215 (262)

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Classification of Foot-and-Mouth and Lumpy Skin Disease in Cattle Using Frozen Pretrained Encoders: A Comparison of Convolutional and Transformer Architectures

Veterinary Sciences
Objective: To determine whether the architectural family of a pretrained encoder, convolutional or attentional, governs its transferability and the reliability of its probabilities under frozen transfer, and how much of the task can be solved once lesion
Paulo Valerio, Wilfredo Ticona
doaj   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Bounding as a remedy for reference-label error in

Forensic Science International: Synergy
The log-likelihood-ratio cost ( C llr ) is the standard metric for validating automated likelihood-ratio (LR) systems in forensic science, justified by its being a strictly proper scoring rule.
Arafat Al-Dhaqm, Kashif Naseer Qureshi, Shukor Abd Razak   +2 more
doaj   +1 more source

Mechanism design for the truthful elicitation of costly probabilistic estimates in distributed information systems [PDF]

, 2010
This paper reports on the design of a novel two-stage mechanism, based on strictly proper scoring rules, that allows a centre to acquire a costly forecast of a future event (such as a meteorological phenomenon or a probabilistic estimate of a specific ...
Gerding, E. H., Enrico H. Gerding, Papakonstantinou, Athanasios, Alex Rogers, Rogers, Alex, Papakonstantinou, A., Jennings, N. R., Rogers, A, Nicholas R. Jennings, Jennings, Nicholas R., Jennings, Nicholas R, Athanasios Papakonstantinou, Gerding, Enrico H, Gerding, Enrico H.   +13 more
core   +1 more source

dynoGP: Deep Gaussian Processes for Dynamic System Identification

International Journal of Adaptive Control and Signal Processing, EarlyView.
This work introduces a novel class of deep models for system identification, dynamical deep Gaussian processes, which combine the strengths of data‐driven methods, such as those based on neural network architectures, with the ability to output a probability distribution for uncertainty representation.
Alessio Benavoli, Marco Forgione, Dario Piga, Marco Zaffalon   +3 more
wiley   +1 more source

Proper scoring rules in epistemic decision theory [PDF]

, 2020
Epistemic decision theory (EpDT) aims to defend a variety of epistemic norms in terms of their facilitation of epistemic ends. One of the most important components of EpDT is known as a scoring rule (used to measure inaccuracies of credences).
WANG, Maomei
core   +1 more source

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

Survival Regression with Proper Scoring Rules and Monotonic Neural Networks

, 2021
We consider frequently used scoring rules for right-censored survival regression models such as time-dependent concordance, survival-CRPS, integrated Brier score and integrated binomial log-likelihood, and prove that neither of them is a proper scoring rule. This means that the true survival distribution may be scored worse than incorrect distributions,
Rindt, D, Hu, R, Steinsaltz, D, Sejdinovic, D   +3 more
openaire   +4 more sources