Results 91 to 100 of about 16,754,236 (393)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Government Property and Government Speech [PDF]

open access: yes, 2011
The relationship between property and speech is close but complicated. Speakers use places and things to deliver their messages, and rely on property rights both to protect expressive acts and to serve as an independent means of expression.
Blocher, Joseph
core   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

The Choice between Formal and Informal Intellectual Property: A Review

open access: yes, 2014
We survey the economic literature, both theoretical and empirical, on the choice of intellectual property protection by firms. Our focus is on the trade-offs between using patents and disclosing versus the use of secrecy, although we also look briefly at
Bronwyn H Hall   +3 more
semanticscholar   +1 more source

Property FA is not a profinite property

open access: yesGroups, Geometry, and Dynamics
We exhibit infinitely many pairs of non-isomorphic finitely presented, residually finite groups \Delta and \Gamma with \Delta having Property FA ...
Tamunonye Cheetham-West   +3 more
openaire   +2 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

On the Property

open access: yes, 2016
We construct a continuous function such that possesses -property, but does not have approximate derivative on a set of full Lebesgue measure. This shows that Banach’s Theorem concerning differentiability of continuous functions with Lusin’s property does
S. Kowalczyk, M. Turowska
semanticscholar   +1 more source

Erie County Property Taxes [PDF]

open access: yes, 2009
It is a tax on the assessed value of real property. Typically set by school boards, town boards, village boards, and city and county governments. Applies to both homeowners and businesses, although rates and exemptions may differ.
Miichalek, Greg
core   +1 more source

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