Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
The Canine Search and Adoption Decision Process: A Conceptual Framework for Companion Pet Shelter Adoption. [PDF]
Animals (Basel)Minnis L, Davis DB.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Necesary changes to valuation practice in China after World Trade Organisation admission
, 2004 This paper outlines the necessary changes in valuation practice after China's admission to the World Trade "Organisation (WTO). After a 15-years marathon negotiation process, China was formally admitted to the WTO in November 2001.
Chan, Hok Kee Nelson
core
Unlocking the financing potential of forest-based carbon assets: a valuation framework for pledge lending under uncertainty in China. [PDF]
Sci RepZhang Y, Zhang J.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
COMMON PROPERTY UNDER MANAGEMENT FLEXIBILITY: VALUATION, OPTIMAL EXPLOITATION, AND REGULATION
Evidence shows that fisheries need close and careful attention because it has been observed that common property fisheries might be blamed for at least two sources of inefficiency.
Maza, Arantza Murillas
core
Contaminated land valuation and the problem of stigma
, 2001 Summary of the thesis: This dissertation is about the valuation of contaminated land and the problem of stigma. The value of contaminated land is to a large extent affectd by statutory regulations.
Chan, Hok Kee Nelson
core
Social mobility in transition. Value repertoires in higher education and moral meanings of the profession among first-generation graduates in Chile. [PDF]
Front SociolTabilo-Prieto I.
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source