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Prophage Genomics [PDF]

open access: yesMicrobiology and Molecular Biology Reviews, 2003
SUMMARY The majority of the bacterial genome sequences deposited in the National Center for Biotechnology Information database contain prophage sequences. Analysis of the prophages suggested that after being integrated into bacterial genomes, they undergo a complex decay process consisting of inactivating point mutations ...
Carlos, Canchaya   +4 more
openaire   +3 more sources

Widespread and largely unknown prophage activity, diversity, and function in two genera of wheat phyllosphere bacteria

open access: yesThe ISME Journal, 2023
Environmental bacteria host an enormous number of prophages, but their diversity and natural functions remain largely elusive. Here, we investigate prophage activity and diversity in 63 Erwinia and Pseudomonas strains isolated from flag leaves of wheat ...
Peter Erdmann Dougherty   +7 more
semanticscholar   +1 more source

Signals triggering prophage induction in the gut microbiota

open access: yesMolecular Microbiology, 2022
Compared to bacteria of the gut microbiota, bacteriophages are still poorly characterised, and their physiological importance is far less known. Temperate phages are probably a major actor in the gut, as it is estimated that 80% of intestinal bacteria ...
Caroline Henrot, M. Petit
semanticscholar   +1 more source

Genome-based identification of active prophage regions by next generation sequencing in Bacillus licheniformis DSM13. [PDF]

open access: yesPLoS ONE, 2015
Prophages are viruses, which have integrated their genomes into the genome of a bacterial host. The status of the prophage genome can vary from fully intact with the potential to form infective particles to a remnant state where only a few phage genes ...
Robert Hertel   +7 more
doaj   +1 more source

Extracellular vesicle formation in Lactococcus lactis is stimulated by prophage‐encoded holin–lysin system

open access: yesMicrobial Biotechnology, 2022
Gram‐positive bacterial extracellular membrane vesicles (EVs) have been drawing more attention in recent years. However, mechanistic insights are still lacking on how EVs are released through the cell walls in Gram‐positive bacteria.
Yue Liu   +5 more
semanticscholar   +1 more source

Diversity of prophage DNA regions of Streptococcus agalactiae clonal lineages from adults and neonates with invasive infectious disease. [PDF]

open access: yesPLoS ONE, 2011
The phylogenetic position and prophage DNA content of the genomes of 142 S. agalactiae (group-B streptococcus, GBS) isolates responsible for bacteremia and meningitis in adults and neonates were studied and compared.
Mazen Salloum   +3 more
doaj   +1 more source

Small protein modules dictate prophage fates during polylysogeny

open access: yesbioRxiv, 2022
 Prophage lysogeny-to-lysis transitions are controlled by regulatory modules consisting of transcription factors and partner small proteins that are activated through DNA-damage-independent pathways, including by quorum sensing, and these modules ...
Justin E. Silpe   +4 more
semanticscholar   +1 more source

CRISPR-Cas Controls Cryptic Prophages [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
The bacterial archetypal adaptive immune system, CRISPR-Cas, is thought to be repressed in the best-studied bacterium, Escherichia coli K-12. We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages.
Sooyeon Song   +6 more
openaire   +2 more sources

Spontaneous Prophage Induction Contributes to the Production of Membrane Vesicles by the Gram-Positive Bacterium Lacticaseibacillus casei BL23

open access: yesmBio, 2022
The last few decades have demonstrated that membrane vesicles (MVs) produced by microorganisms can have a wide variety of functions. This diversity places MVs at the crossroads of major research topics in current microbiology such as antibiotic ...
David da Silva Barreira   +5 more
semanticscholar   +1 more source

Increased whiB7 expression and antibiotic resistance in Mycobacterium chelonae carrying two prophages

open access: yesBMC Microbiology, 2021
Background The global rise in the incidence of non-tuberculosis mycobacterial infections is of increasing concern due their high levels of intrinsic antibiotic resistance.
Jaycee Cushman   +5 more
doaj   +1 more source

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