Results 61 to 70 of about 39,319 (207)

Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells

Advanced Science, EarlyView.
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh, Payel Bhanja, Emily Schueddig, Jufri Setianegara, Yuting Lin, Kenny Guida, Shujah Rehman, Stacey Krepel, Devin Koestler, Ronald C. Chen, Katherine L. Cook, Subhrajit Saha   +11 more
wiley   +1 more source

Gene content, phage cycle regulation model and prophage inactivation disclosed by prophage genomics in the Helicobacter pylori Genome Project

Gut Microbes
Prophages can have major clinical implications through their ability to change pathogenic bacterial traits. There is limited understanding of the prophage role in ecological, evolutionary, adaptive processes and pathogenicity of Helicobacter pylori, a ...
Filipa F. Vale, Richard J. Roberts, Ichizo Kobayashi, M. Constanza Camargo, Charles S. Rabkin   +4 more
doaj   +1 more source

Molecular bases and role of viruses in the human microbiome. [PDF]

, 2014
Viruses are dependent biological entities that interact with the genetic material of most cells on the planet, including the trillions within the human microbiome.
Abeles, Shira R, Pride, David T
core   +1 more source

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

Advanced Science, EarlyView.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang, Heqi Wu, Mengqi Qu, Chunge Zhang, Ziqian Xu, Yuhang Pei, Chaochao Zhao, Jiangtao Wang, Sufang Ma, Na Lyu, Xuebin Xu, Yuhai Bi, Baoli Zhu, George F. Gao   +13 more
wiley   +1 more source

Host population structure and species resolution reveal prophage transmission dynamics

mBio
Much knowledge about bacteriophages has been obtained via genomics and metagenomics over the last decades. However, most studies dealing with prophage diversity have rarely conducted phage species delimitation (aspect 1) and have hardly integrated the ...
Karen Tenorio-Carnalla, Alejandro Aguilar-Vera, Alfredo J. Hernández-Alvarez, Gamaliel López-Leal, Valeria Mateo-Estrada, Rosa Isela Santamaria, Santiago Castillo-Ramírez   +6 more
doaj   +1 more source

Inhibition of Shiga toxin-converting bacteriophage development by novel antioxidant compounds [PDF]

, 2018
Oxidative stress may be the major cause of induction of Shiga toxin-converting (Stx) prophages from chromosomes of Shiga toxin-producing Escherichia coli (STEC) in human intestine.
Bloch, Sylwia, Bouaziz, Zouhair, Jose, Joachim, Le Borgne, Marc, Marminon, Christelle, Nebois, Pascal, Nejman-Faleńczyk, Bożena, Pierzynowska, Karolina, Piotrowska, Ewa, Saso, Luciano, Węgrzyn, Alicja, Węgrzyn, Grzegorz   +11 more
core   +1 more source

An ultraviolet–visible spectroscopy system for studying real‐time pressure effects on enzyme activity

Limnology and Oceanography: Methods, EarlyView.
Abstract Investigations of hydrostatic pressure effects on microbial enzymatic processing are challenging but critical for understanding element cycling in the world's oceans. In this study, we developed and tested a stainless‐steel pressure cell capable of withstanding up to 110 MPa of hydrostatic pressure (equivalent to ~ 11,000 m depth), featuring ...
Maria Papadimitraki, Urban Wünsch, John Paul Balmonte, Mathias Middelboe, Colin A. Stedmon, Karl M. Attard, Ronnie N. Glud   +6 more
wiley   +1 more source

Profile of Eight Prophage Sequences Present in the Genomes of Different Acinetobacter baumannii Strains

Medical Laboratory Journal, 2017
Background and Objective: Prophage sequences are major contributors to interstrain variations within the same bacterial species. Acinetobacter baumannii is a gram-negative bacterium that causes a wide range of nosocomial infections, especially in ...
Nima Shaykh Baygloo, Majid Bouzari, Fateh Rahimi   +2 more
doaj  

Fixed points and limit cycles in the population dynamics of lysogenic viruses and their hosts

, 2010
Starting with stochastic rate equations for the fundamental interactions between microbes and their viruses, we derive a mean field theory for the population dynamics of microbe-virus systems, including the effects of lysogeny. In the absence of lysogeny,
A. Kolmogorov, A. Marr, A. Wallace, J. Smith, J. Weitz, M. Ptashne, Nigel Goldenfeld, Zhenyu Wang   +7 more
core   +1 more source

Prophages are gut virome pioneers [PDF]

Nature Reviews Microbiology, 2020
A recent study shows that assembly of gut viral communities in early life occurs in distinct steps and is modulated by breastfeeding.
openaire   +2 more sources