Results 71 to 80 of about 18,160 (174)

Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]

, 2017
The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core   +1 more source

Host Factor Induced Bacterial Extracellular Vesicles Promote Horizontal Gene Transfer in Vibrio cholerae

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
Antimicrobial stressors, that is, bile or mitomycin C, induce enlarged, nucleic acid‐rich bacterial extracellular vesicles in Vibrio cholerae that facilitate horizontal gene transfer in vitro and during intestinal colonisation. The findings provide a detailed comparison of control versus stress‐induced vesicles, identify bile as a host factor shaping ...
Dominik Fleischhacker, Yi‐Chi Chen, Noa Sanchez Gordo, Amar Cosic, Ratchara Kalwong, Leo Eberl, Stefan Schild   +6 more
wiley   +1 more source

Analysis of intact prophages in genomes of Paenibacillus larvae: An important pathogen for bees

Frontiers in Microbiology, 2022
Paenibacillus larvae is the etiological agent of American Foulbrood (AFB), a highly contagious and worldwide spread bacterial disease that affects honeybee brood. In this study, all complete P.
Henrique G. Ribeiro, Henrique G. Ribeiro, Anna Nilsson, Luís D. R. Melo, Luís D. R. Melo, Ana Oliveira, Ana Oliveira   +6 more
doaj   +1 more source

Gene silencing and large-scale domain structure of the E. coli genome

, 2012
The H-NS chromosome-organizing protein in E. coli can stabilize genomic DNA loops, and form oligomeric structures connected to repression of gene expression.
Lagomarsino, Marco Cosentino, Sclavi, Bianca, Zarei, Mina   +2 more
core   +3 more sources

Horizontal DNA transfer mechanisms of bacteria as weapons of intragenomic conflict [PDF]

, 2016
Horizontal DNA transfer (HDT) is a pervasive mechanism of diversification in many microbial species, but its primary evolutionary role remains controversial.
A Adams, A Adams, AB Dalia, AI Khan, B Martin, BJ Haijema, BR Levin, C Boutry, C Buchrieser, C Camacho, C Canchaya, C Chewapreecha, C Fraser, C Johnston, C Johnston, C Johnston, Christophe Fraser, Christopher Wymant, CS Wylie, D Dubnau, D Hyatt, DA Baltrus, DA Caugant, DA Higgins, DA Morrison, DA Morrison, DE Fouts, DJP Engelmoer, E Borezee, E Szathmáry, E V Pestova, E Zaccaria, EA Campbell, EJ Feil, EJ Gaasbeek, EJ Gaasbeek, EP Rocha, ES Antonova, F Ginetti, F Griffith, F Liu, GG Wilson, GJ Stewart, GM Süel, GW Goldberg, H Bagci, H Bernstein, H Deveau, H Li, H Maamar, H Muller, H Ochman, H Tong, H-H Chou, HC Neu, I Chen, I Mortier-Barriere, I Mortier-Barrière, J Bondy-Denomy, J Guglielmini, J Majewski, J Majewski, J-P Claverys, JA Lanie, JA Londoño-Vallejo, JA Mongold, JC Lefevre, JC Mell, JH Stuy, JJ Sakamoto, JK Setlow, JM Auchtung, JM Musser, JM Smith, JM Smith, JO McInerney, JP Claverys, JP Claverys, JT Simpson, JW Beaber, K Turgay, KS Makarova, KT Konstantinidis, L Attaiech, L Fontaine, L Van Valen, L-M Bobay, LP Macfadyen, LS Frost, LS Håvarstein, LS Håvarstein, M Berge, M Boetzer, M Del Grosso, M Prudhomme, M Ramirez, MA Hoelzer, ME Kahn, MF Wojciechowski, MJ Lopez-Sanchez, ML Gwinn, MR Oggioni, MS Dorer, MTG Holden, Nicholas J. Croucher, Nick H. Barton, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, NJ Croucher, O Johnsborg, OE Cornejo, OH Ambur, OT Avery, P Glaser, P Jorth, P Luo, PA Levin, Paul Turner, PJ Johnsen, R Davidoff-Abelson, R Edgar, R Mostowy, RA Fisher, Rafal Mostowy, RE Michod, RE Yasbin, RJ Redfield, RJ Redfield, RJ Redfield, RJ Redfield, RJ Redfield, RJ Redfield, RK Aziz, RP Novick, S Lacks, SA McMahon, SB Beres, SE Finkel, SJ Labrie, SP Otto, Stephen D. Bentley, T Carver, T Nozawa, U Munoz-Najar, WA Sweetman, WJ Kent, X Charpentier, X Charpentier, X Didelot, Y Li, Z Zhou   +157 more
core   +3 more sources

An ultraviolet–visible spectroscopy system for studying real‐time pressure effects on enzyme activity

Limnology and Oceanography: Methods, Volume 24, Issue 5, May 2026.
Abstract Investigations of hydrostatic pressure effects on microbial enzymatic processing are challenging but critical for understanding element cycling in the world's oceans. In this study, we developed and tested a stainless‐steel pressure cell capable of withstanding up to 110 MPa of hydrostatic pressure (equivalent to ~ 11,000 m depth), featuring ...
Maria Papadimitraki, Urban Wünsch, John Paul Balmonte, Mathias Middelboe, Colin A. Stedmon, Karl M. Attard, Ronnie N. Glud   +6 more
wiley   +1 more source

Comprehensive deciphering prophages in genus Acetobacter on the ecology, genomic features, toxin–antitoxin system, and linkage with CRISPR-Cas system

Frontiers in Microbiology, 2022
Acetobacter is the predominant microbe in vinegar production, particularly in those natural fermentations that are achieved by complex microbial communities.
Chenggong Qian, Jiawen Ma, Jiale Liang, Lei Zhang, Xinle Liang   +4 more
doaj   +1 more source

Genomic analysis of 48 paenibacillus larvae bacteriophages [PDF]

, 2018
Indexación: Scopus.Funding: Research at UNLV was funded by National Institute of General Medical Sciences grant GM103440 (NV INBRE), the UNLV School of Life Sciences, and the UNLV College of Sciences. E.C.-N.
Castro-Nallar, E., Fajardo, C.P., Grose, J.H., Hope, S., Mendez, K.N., Stamereilers, C., Tsourkas, P.K., Walker, J.K.   +7 more
core   +1 more source

A ‘Genome‐First’ Framework for Next‐Generation Bioinputs: From Functional Mining to Rational Synthetic Microbial Communities

Environmental Microbiology, Volume 28, Issue 5, May 2026.
I propose a ‘genome‐first’ framework to collapse the phenotypic bottleneck in bioinput discovery. By integrating multi‐layered genome mining and reverse ecology, this paradigm enables the rational design of stable synthetic microbial communities for a data‐driven and sustainable agricultural bioeconomy.
Osiel Silva Gonçalves
wiley   +1 more source

Programmable Klebsiella pneumoniae Phage Tropism Enabled by Scalable Receptor‐Binding Protein Mining and Modular Assembly

Advanced Science, Volume 13, Issue 21, 13 April 2026.
This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing, Yiyao Song, Xianbiao Bi, Yuqin Song, Dawei Wei, Jiangqing Huang, Yuan Zeng, Gang Zhang, Rong Zhang, Chao Wang, Jie Feng   +10 more
wiley   +1 more source