Results 81 to 90 of about 33,387 (250)

Prophage-Mediated Disruption of Genetic Competence in Staphylococcus pseudintermedius

mSystems, 2020
Staphylococcus pseudintermedius is a bacterium responsible for clinically important infections in dogs and can infect humans. In this study, we performed genomic analysis of 371 S.
M. R. Brooks, Lyan Padilla-Vélez, Tarannum A. Khan, Azaan A. Qureshi, J. Pieper, C. Maddox, Md Tauqeer Alam   +6 more
semanticscholar   +1 more source

Mycobacteriophage Mcgavigan Uses Noncanonical Bxb1‐Like Repressor for Heterotypic Superinfection Immunity

Journal of Basic Microbiology, Volume 66, Issue 1, January 2026.
ABSTRACT Mycobacteriophage Mcgavigan could be a promising candidate for use as a preventative agent against infections with Mycobacterium avium subsp. paratuberculosis. Bioinformatic analysis of the Mcgavigan genome revealed the presence of an operon containing a “Bxb1‐like” repressor.
Natali Shafer, Bradley E. Dubrule, Jeroen De Buck   +2 more
wiley   +1 more source

Functional Relevance of CASP16 Nucleic Acid Predictions as Evaluated by Structure Providers

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 1, Page 51-78, January 2026.
ABSTRACT Accurate biomolecular structure prediction enables the prediction of mutational effects, the speculation of function based on predicted structural homology, the analysis of ligand binding modes, experimental model building, and many other applications.
Rachael C. Kretsch, Reinhard Albrecht, Ebbe S. Andersen, Hsuan‐Ai Chen, Wah Chiu, Rhiju Das, Jeanine G. Gezelle, Marcus D. Hartmann, Claudia Höbartner, Yimin Hu, Shekhar Jadhav, Philip E. Johnson, Christopher P. Jones, Deepak Koirala, Emil L. Kristoffersen, Eric Largy, Anna Lewicka, Cameron D. Mackereth, Marco Marcia, Michela Nigro, Manju Ojha, Joseph A. Piccirilli, Phoebe A. Rice, Heewhan Shin, Anna‐Lena Steckelberg, Zhaoming Su, Yoshita Srivastava, Liu Wang, Yuan Wu, Jiahao Xie, Nikolaj H. Zwergius, John Moult, Andriy Kryshtafovych   +32 more
wiley   +1 more source

DBSCAN-SWA: An Integrated Tool for Rapid Prophage Detection and Annotation

bioRxiv, 2020
Summary As an intracellular form of a bacteriophage in the bacterial host genome, a prophage is usually integrated into bacterial DNA with high specificity and contributes to horizontal gene transfer (HGT).
R. Gan, Fengxia Zhou, Yu Si, Han Yang, Chuangeng Chen, Jiqiu Wu, Fan Zhang, Zhiwei Huang   +7 more
semanticscholar   +1 more source

Facing the D‐Ilemma of Heat Resistance Parameters: From Pathogen Risk Assessment to Surrogate Selection Challenges in the Fruit Juice and Nectar Production

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT Over the years, numerous D‐ and z‐values have been published in the scientific literature. While these values initially appear to be valid criteria for assessing and comparing the heat resistance of different microorganisms under the same conditions or the same microorganism under different conditions, this is not always the case.
Astrid Gędas, Agnes Weiss
wiley   +1 more source

Genotyping and characterization of prophage patterns in clinical isolates of Staphylococcus aureus

BMC Research Notes, 2019
Objective Staphylococcus aureus is considered an important pathogen with a variety of virulence factors in communities and hospitals all around the world. Prophage typing is a practical technique for categorizing this bacterium. In this study, we focused
Mahya Dini, Leili Shokoohizadeh, Farid Aziz Jalilian, Abbas Moradi, Mohammad Reza Arabestani   +4 more
doaj   +1 more source

Active Lysogeny in Listeria Monocytogenes Is a Bacteria-Phage Adaptive Response in the Mammalian Environment

Cell Reports, 2020
Summary: Some Listeria monocytogenes (Lm) strains harbor a prophage within the comK gene, which renders it inactive. During Lm infection of macrophage cells, the prophage turns into a molecular switch, promoting comK gene expression and therefore Lm ...
Anna Pasechnek, Lev Rabinovich, Olga Stadnyuk, Gil Azulay, Jessica Mioduser, Tal Argov, Ilya Borovok, Nadejda Sigal, Anat A. Herskovits   +8 more
doaj   +1 more source

Rapid Identification of Superior Endogenous Signal Peptides for Heterologous Protein Secretion by Corynebacterium glutamicum Through Modular Cloning and Automation

Microbial Biotechnology, Volume 19, Issue 1, January 2026.
A modular cloning approach combined with an automated high‐throughput platform enabled rapid identification of superior endogenous signal peptides for the secretion of proteins of interest (POIs), such as industrial enzymes, by Corynebacterium glutamicum. This streamlined workflow accelerates discovery and development of efficient bacterial systems for
Susana Matamouros, Julia Tenhaef, Astrid Bida, Stephan Noack, Michael Bott   +4 more
wiley   +1 more source

Cutting out the φC31 prophage [PDF]

Molecular Microbiology, 2011
SummaryTo establish a lysogenic lifestyle, the temperate bacteriophage φC31 integrates its genome into the chromosome of its Streptomyces host, by site‐specific recombination between attP (the attachment site in the phage DNA) and attB (the chromosomal attachment site). This reaction is promoted by a phage‐encoded serine recombinase Int.
openaire   +2 more sources

Prophage induction is enhanced and required for renal disease and lethality in an EHEC mouse model.

PLoS Pathogens, 2013
Enterohemorrhagic Escherichia coli (EHEC), particularly serotype O157:H7, causes hemorrhagic colitis, hemolytic uremic syndrome, and even death. In vitro studies showed that Shiga toxin 2 (Stx2), the primary virulence factor expressed by EDL933 (an O157 ...
Jessica S Tyler, Karen Beeri, Jared L Reynolds, Christopher J Alteri, Katherine G Skinner, Jonathan H Friedman, Kathryn A Eaton, David I Friedman   +7 more
doaj   +1 more source