Results 11 to 20 of about 13,992 (159)

Deciphering Active Prophages from Metagenomes [PDF]

mSystems, 2022
Temperate phages (prophages) are ubiquitous in nature and persist as dormant components of host cells (lysogenic stage) before activating and lysing the host (lytic stage). Actively replicating prophages contribute to central community processes, such as
Kristopher Kieft, Karthik Anantharaman
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Campylobacter prophage diversity reveals pervasive recombination between prophages from different Campylobacter species

Microbiology Spectrum
Prophages, bacteriophages integrated into bacterial genomes, play a critical role in the genetic diversity and evolution of bacterial species. In this study, we investigated the prophage population harbored in Campylobacter species.
Adán Manuel Piña-González, Hugo G. Castelán-Sánchez, Juan Manuel Hurtado-Ramírez, Gamaliel López-Leal   +3 more
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Prophage Genomics [PDF]

Microbiology and Molecular Biology Reviews, 2003
SUMMARY The majority of the bacterial genome sequences deposited in the National Center for Biotechnology Information database contain prophage sequences. Analysis of the prophages suggested that after being integrated into bacterial genomes, they undergo a complex decay process consisting of inactivating point mutations ...
Carlos, Canchaya, Caroline, Proux, Ghislain, Fournous, Anne, Bruttin, Harald, Brüssow   +4 more
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Diversity of Pseudomonas aeruginosa Temperate Phages

mSphere, 2022
Modern sequencing technologies have provided insight into the genetic diversity of numerous species, including the human pathogen Pseudomonas aeruginosa.
Genevieve Johnson, Swarnali Banerjee, Catherine Putonti   +2 more
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In Silico Characterisation of Putative Prophages in Lactobacillaceae Used in Probiotics for Vaginal Health

Microorganisms, 2022
While live biotherapeutics offer a promising approach to optimizing vaginal microbiota, the presence of functional prophages within introduced Lactobacillaceae strains could impact their safety and efficacy.
Anna-Ursula Happel, Brian R. Kullin, Hoyam Gamieldien, Heather B. Jaspan, Arvind Varsani, Darren Martin, Jo-Ann S. Passmore, Rémy Froissart   +7 more
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Comprehensive deciphering prophages in genus Acetobacter on the ecology, genomic features, toxin–antitoxin system, and linkage with CRISPR-Cas system

Frontiers in Microbiology, 2022
Acetobacter is the predominant microbe in vinegar production, particularly in those natural fermentations that are achieved by complex microbial communities.
Chenggong Qian, Jiawen Ma, Jiale Liang, Lei Zhang, Xinle Liang   +4 more
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Prophage Hunter: an integrative hunting tool for active prophages [PDF]

Nucleic Acids Research, 2019
Abstract Identifying active prophages is critical for studying coevolution of phage and bacteria, investigating phage physiology and biochemistry, and engineering designer phages for diverse applications. We present Prophage Hunter, a tool aimed at hunting for active prophages from whole genome assembly of bacteria.
Wenchen Song, Hai-Xi Sun, Carolyn Zhang, Li Cheng, Ye Peng, Ziqing Deng, Dan Wang, Yun Wang, Ming Hu, Wenen Liu, Huanming Yang, Yue Shen, Junhua Li, Lingchong You, Minfeng Xiao   +14 more
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CRISPR-Cas Controls Cryptic Prophages [PDF]

International Journal of Molecular Sciences, 2021
The bacterial archetypal adaptive immune system, CRISPR-Cas, is thought to be repressed in the best-studied bacterium, Escherichia coli K-12. We show here that the E. coli CRISPR-Cas system is active and serves to inhibit its nine defective (i.e., cryptic) prophages.
Sooyeon Song, Ekaterina Semenova, Konstantin Severinov, Laura Fernández-García, Michael J. Benedik, Toshinari Maeda, Thomas K. Wood   +6 more
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Prophage identification and molecular analysis in the genomes of Pseudomonas aeruginosa strains isolated from critical care patients

mSphere, 2023
Prophages are bacteriophages integrated into the bacterial host’s chromosome. This research aims to analyze and characterize the existing prophages within a collection of 53 Pseudomonas aeruginosa strains from intensive care units (ICUs) in Portugal and ...
Manuel González de Aledo, Lucia Blasco, Maria Lopez, Concha Ortiz-Cartagena, Inés Bleriot, Olga Pacios, Marta Hernández-García, Rafael Cantón, Maria Tomas   +8 more
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Prediction and characterization of prophages of Stenotrophomonas maltophilia reveals a remarkable phylogenetic diversity of prophages

Scientific Reports, 2023
Prophages, which enables bacterial hosts to acquire novel traits, and increase genetic variation and evolutionary innovation, are considered to be one of the greatest drivers of bacterial diversity and evolution.
Zheng Fang, Man Xu, Shan Shen, Weiwei Sun, Qing Yu, Qingshan Wu, Lan Xiang, Qingbei Weng   +7 more
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