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Chromosome Organization in Early Meiotic Prophase [PDF]
Frontiers in Cell and Developmental Biology, 2021 One of the most fascinating aspects of meiosis is the extensive reorganization of the genome at the prophase of the first meiotic division (prophase I). The first steps of this reorganization are observed with the establishment of an axis structure, that
Corinne Grey, Bernard de Massy
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Phospho-Regulation of Meiotic Prophase [PDF]
Frontiers in Cell and Developmental Biology, 2021 Germ cells undergoing meiosis rely on an intricate network of surveillance mechanisms that govern the production of euploid gametes for successful sexual reproduction.
Funda M. Kar, Andreas Hochwagen
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Regulation of Meiotic Prophase One in Mammalian Oocytes [PDF]
Frontiers in Cell and Developmental Biology, 2021 In female mammals, meiotic prophase one begins during fetal development. Oocytes transition through the prophase one substages consisting of leptotene, zygotene, and pachytene, and are finally arrested at the diplotene substage, for months in mice and ...
Xiaoyi Wang, Melissa E. Pepling
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Meioc maintains an extended meiotic prophase I in mice. [PDF]
PLoS Genetics, 2017 The meiosis-specific chromosomal events of homolog pairing, synapsis, and recombination occur over an extended meiotic prophase I that is many times longer than prophase of mitosis.
Y Q Shirleen Soh +5 more
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PLoS Genetics, 2021 During gametogenesis in mammals, meiosis ensures the production of haploid gametes. The timing and length of meiosis to produce female and male gametes differ considerably. In contrast to males, meiotic prophase I in females initiates during development.
Xueying Fan +12 more
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Dynamic Reorganization of the Genome Shapes the Recombination Landscape in Meiotic Prophase [PDF]
Nature Structural & Molecular Biology, 2019 In meiotic prophase, chromosomes are organized into compacted loop arrays to promote homolog pairing and recombination. Here, we probe the architecture of the mouse spermatocyte genome in early and late meiotic prophase using chromosome conformation ...
Lucas Patel +9 more
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Distinct prophase arrest mechanisms in human male meiosis [PDF]
Development, 2017 To prevent chromosomal aberrations being transmitted to the offspring, strict meiotic checkpoints are in place to remove aberrant spermatocytes. However, in about 1% of males these checkpoints cause complete meiotic arrest leading to azoospermia and ...
Sabrina Z. Jan +6 more
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Barley Anther and Meiocyte Transcriptome Dynamics in Meiotic Prophase I
Frontiers in Plant Science, 2021 In flowering plants, successful germinal cell development and meiotic recombination depend upon a combination of environmental and genetic factors. To gain insights into this specialized reproductive development program we used short- and long-read RNA ...
Abdellah Barakate +13 more
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PLoS Genetics, 2019 Sister chromatid cohesion on chromosome arms is essential for the segregation of homologous chromosomes during meiosis I while it is dispensable for sister chromatid separation during mitosis.
Kiran Challa +5 more
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Condensation patterns of prophase/prometaphase chromosome are correlated with H4K5 histone acetylation and genomic DNA contents in plants. [PDF]
PLoS ONE, 2017 Mitotic prophase chromosome condensation plays an essential role in nuclear division being therefore regulated by highly conserved mechanisms. However, degrees of chromatin condensation in prophase-prometaphase cells may vary along the chromosomes ...
Lidiane Feitoza +2 more
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