Results 191 to 200 of about 537,181 (284)

Inflammation‐driven variability in drug metabolism: Insights from voriconazole treatment of HSCT recipients

British Journal of Clinical Pharmacology, EarlyView.
Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp, Martijn L. Manson, Henk‐Jan Guchelaar, Stefan Böhringer, Esther H. M. van Egmond, Peter A. von dem Borne, Jesse J. Swen   +6 more
wiley   +1 more source

Patient perspectives on post-operative direct oral anticoagulant for venous thromboembolism prevention in patients with gynecologic cancers undergoing laparotomy. [PDF]

Gynecol Oncol Rep
Black KA, Mateshaytis J, Sevick L, Rogers J, Bisch SP, Flasha P, Pin S.   +6 more
europepmc   +1 more source

Revisiting the Ethics of Urate‐Lowering Therapy Clinical Trials for Gout Management

Arthritis &Rheumatology, EarlyView.
Lisa K. Stamp, Dien Ho, Nicola Dalbeth
wiley   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Timing, risk, and reality: early venous thromboembolism chemoprophylaxis in patients with TBI requiring operative intervention. [PDF]

Trauma Surg Acute Care Open
Dhillon NK.
europepmc   +1 more source

Improved survival after acute graft-versus-host disease diagnosis in the modern era [PDF]

, 2017
et al.,, Hayashi, Robert J, Vig, Ravi
core   +1 more source

Real‐Time Monitoring of In Vitro Transcription for Production of mRNA Using Raman Spectroscopy

Biotechnology and Bioengineering, EarlyView.
Schematic depicting the workflow for model building and validation using Raman spectroscopy for real‐time monitoring of IVT. ABSTRACT The success of COVID‐19 mRNA vaccines showcased the transformative potential of this adaptable, plug‐and‐play, and rapid response platform.
Julia Puppin Chaves Fulber, Xingge Xu, Hadi El Radi, Kevin Grollier, Amine A. Kamen   +4 more
wiley   +1 more source

Prevalence and factors associated with use of prophylaxis for HIV and sexually transmitted infections among sexual health service attendees in England: findings from a cross-sectional observational study. [PDF]

BMJ Public Health
Bell J, Kohli M, Pulford C, Ogaz D, Williams E, Apea V, David N, Suonpera E, Gilson R, Mercer CH, Hughes G, Dunn D, Showler E, Mohammed H, Saunders J.   +14 more
europepmc   +1 more source

Rezafungin as Primary Prophylaxis of <i>Pneumocystis jirovecii</i> Pneumonia in a Critically Ill Person Presenting with AIDS with Trimethoprim/Sulfamethoxazole Allergy: A Case Report. [PDF]

J Fungi (Basel)
Bottanelli M, Mulè A, Molteni C, Gerbi M, Zago MP, Volpi S, Pettenuzzo S, Pandolfo A, Morena V, Gemignani N, Fogliata M, Conti F, Consonni A, Bradanini L, Pontiggia S, Piconi S.   +15 more
europepmc   +1 more source

Lifetime Cost-Utility Analysis of Emicizumab Prophylaxis in Severe Haemophilia A Without Inhibitors in China: A Markov Model Analysis. [PDF]

Haemophilia
Bao H, Bührer C, Lin Z, Zhou L, Xia Y, Jin X, Xuan J.   +6 more
europepmc   +1 more source