Results 41 to 50 of about 540,753 (335)

Effect of Preemptive Therapy vs Antiviral Prophylaxis on Cytomegalovirus Disease in Seronegative Liver Transplant Recipients With Seropositive Donors: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2020
Importance Despite the use of a cytomegalovirus (CMV) prevention strategy of antiviral prophylaxis for high-risk CMV-seronegative liver transplant recipients with seropositive donors, high rates of delayed-onset postprophylaxis CMV disease occur.
Nina Singh, Drew J. Winston, R. Razonable, G. M. Lyon, Fernanda P. Silveira, Marilyn M. Wagener, T. Stevens-Ayers, Bradley C. Edmison, M. Boeckh, Ajit P. Limaye   +9 more
semanticscholar   +1 more source

Some Peculiarities in the Dose Dependence of Separate and Combined In Vitro Cardiotoxicity Effects Induced by CdS and PbS Nanoparticles With Special Attention to Hormesis Manifestations

Dose-Response, 2020
Spherical nanoparticles (NPs) of cadmium and lead sulfides (diameter 37 ± 5 and 24 ± 4 nm, respectively) have been found to be cytotoxic for HL-1 cardiomyocytes as evidenced by decrease in adenosine triphosphate–dependent luminescence.
Vladimir Panov, Ilzira Minigalieva, Tatiana Bushueva, Eleonore Fröhlich, Claudia Meindl, Markus Absenger-Novak, Vladimir Shur, Ekaterina Shishkina, Vladimir Gurvich, Larisa Privalova, Boris A. Katsnelson   +10 more
doaj   +1 more source

Machine Learning-Empowered FTIR Spectroscopy Serum Analysis Stratifies Healthy, Allergic, and SIT-Treated Mice and Humans

Biomolecules, 2020
The unabated global increase of allergic patients leads to an unmet need for rapid and inexpensive tools for the diagnosis of allergies and for monitoring the outcome of allergen-specific immunotherapy (SIT).
Elke Korb, Murat Bağcıoğlu, Erika Garner-Spitzer, Ursula Wiedermann, Monika Ehling-Schulz, Irma Schabussova   +5 more
doaj   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

A multicenter, open-label, phase 3 study of emicizumab prophylaxis in children with hemophilia A with inhibitors.

Blood, 2019
Emicizumab, a bispecific humanized monoclonal antibody, bridges activated factor (F) IX and FX to restore the function of missing activated FVIII in hemophilia A.
G. Young, R. Liesner, Tiffany Y. Chang, R. Sidonio, J. Oldenburg, V. Jiménez‐Yuste, J. Mahlangu, R. Kruse-Jarres, Michael Wang, Marianne Uguen, M. Doral, Lilyan Y. Wright, C. Schmitt, G. Levy, M. Shima, M. Mancuso   +15 more
semanticscholar   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

EPIDEMIC SITUATION FOR HIV-INFECTION IN SIBERIAN FEDERAL REGION IN 2014

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Analyze main epidemiologic indicators for HIV-infection on the territory of SFR for the period from 2012 to 2014 with allotment of contributions of regions into the epidemic for development of personalized regional program for further containment of
E. S. Dovgopolyuk, L. V. Puzyreva, A. D. Safonov, A. V. Mordyk, A. T. Tyumentsev, L. I. Levakhina, G. A. Kalacheva   +6 more
doaj   +1 more source

Toxic Kidney Damage in Rats Following Subchronic Intraperitoneal Exposure to Element Oxide Nanoparticles

Toxics, 2023
Chronic diseases of the urogenital tract, such as bladder cancer, prostate cancer, reproductive disorders, and nephropathies, can develop under the effects of chemical hazards in the working environment.
Yuliya V. Ryabova, Ilzira A. Minigalieva, Marina P. Sutunkova, Svetlana V. Klinova, Alexandra K. Tsaplina, Irene E. Valamina, Ekaterina M. Petrunina, Aristides M. Tsatsakis, Charalampos Mamoulakis, Kostas Stylianou, Sergey V. Kuzmin, Larisa I. Privalova, Boris A. Katsnelson   +12 more
doaj   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

ASSOCIATION OF CERTAIN SINGLE NUCLEOTIDE POLYMORPHISM GENES OF APOPTOSIS SYSTEM WITH A RISK OF DEVELOPMENT OF COLORECTAL CANCER IN RUSSIAN POPULATION

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Study the effect of single nucleotide polymorphism genes TP53 (rsl042522, rsl 800371), CDKN2A (rs3731217, rs3088440) and MDM2 (rs2279744) on the risk of development of colorectal cancer (CRC) in population of Perm Region. Materials and methods. Case
M. Kh. Alyeva, S. Ya. Zverev, I. V. Feldblyum, E. Yu. Noskova, A. O. Kanina, N. I. Markovich   +5 more
doaj   +1 more source