Results 61 to 70 of about 540,753 (335)

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic   +6 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Experience in Providing Medical Assistance to the Population of the Amur Region Exposed to the Effects of the Flood

open access: yesПроблемы особо опасных инфекций, 2014
Medical assistance to individuals residing in the flooded areas of the region was delivered on a priority basis throughout the health care institutions on the territorial-division principle, at the temporal accommodation sites, further on - long-term ...
N. L. Tezikov   +4 more
doaj   +1 more source

EPIDEMIOLOGICAL PREDICTION OF INTESTINAL INFECTION CAUSED BY SOME NON-POLIOENTEROVIRUSES OF COXSACKIE GROUP A AMONG THE POPULATION OF AZERBAIJAN FOR 2015–2024

open access: yesSiberian Journal of Life Sciences and Agriculture, 2022
Background. Despite significant achievements in research and diagnostic practice, as well as in the field of Molecular and Biological Technology, the problem of non-polioenterovirus infections is still at the stage of serious research. Purpose.
Lala I. Rustamova
doaj   +1 more source

Increased Blood Levels of NfL, GFAP, and Placental Growth Factor After Radiotherapy to the Brain

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this study, we analyzed biomarkers of neuronal, glial, and vascular injury in longitudinal paired samples of blood and cerebrospinal fluid after prophylactic cranial irradiation in patients with small cell lung cancer. Neurofilament light chain protein (NfL) and glial fibrillary acidic protein (GFAP) increased in serum and cerebrospinal ...
Erik Fernström   +5 more
wiley   +1 more source

The most important inferences from the Ekaterinburg nanotoxicology team’s animal experiments assessing adverse health effects of metallic and metal oxide nanoparticles

open access: yesToxicology Reports, 2018
During 2009–2017 we have studied nanoparticles of elemental silver or gold and of iron, copper, nickel, manganese, lead, zinc, aluminium and titanium oxides (Me-NPs) using, in most cases, a single low-dose intratracheal instillation 24 h before the ...
Marina P. Sutunkova   +5 more
doaj   +1 more source

Health Outcomes of Judo Training as an Organized Physical Activity for Children and Adolescents: A Literature Review

open access: yesChildren, 2023
Judo, an organized physical activity for children and adolescents, has gained popularity worldwide. Physical activity is vital during times of rising obesity and a sedentary lifestyle in this age group. The article aims to review the current knowledge of
Monika Kowalczyk   +2 more
doaj   +1 more source

Young adult outcomes of childhood prophylaxis for severe hemophilia A: results of the Joint Outcome Continuation Study.

open access: yesBlood Advances, 2020
The Joint Outcome Study (JOS), a randomized controlled trial, demonstrated that children with severe hemophilia A (HA) initiating prophylactic factor VIII (FVIII) prior to age 2.5 years had reduced joint damage at age 6 years compared with those treated ...
B. Warren   +12 more
semanticscholar   +1 more source

Improvements in Health‐Related Quality of Life With Treat‐to‐Target Urate‐Lowering Therapy in Gout: A Post Hoc Analysis of a Randomized Multicenter Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Although treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL ...
Austin Barry   +16 more
wiley   +1 more source

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