Results 161 to 170 of about 4,243 (197)

The Bacterial Metabolite Lndole-3-Propionic Acid Alleviates Acetaminophen-Induced Acute Liver Injury Partly through the Aryl Hydrocarbon Receptor Pathway. [PDF]

J Microbiol Biotechnol
Zhou B, Ye X, Tian Y, Wang X, Xu X, Ren Y.   +5 more
europepmc   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

The FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati, Chandra Sekhar Yadavalli, Md Monirul Hoque, Swapna Thota, Gadiparthi N. Rao   +4 more
wiley   +1 more source

Machine-Learning-Assisted Pathway Optimization in Large Combinatorial Design Spaces: A p-Coumaric Acid Case Study. [PDF]

ACS Synth Biol
van Lent P, van der Hoek R, Moreno Paz S, Kooi I, Jonkers M, Zwartjens P, Schmitz J, Abeel T.   +7 more
europepmc   +1 more source

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

The FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki, Timothy D. Niepokny, Tina Khalilzadehsabet, Elizabeth Dumais, Nicolas Flamand, Vincenzo Di Marzo, Eric M. Mintz, Cristoforo Silvestri   +7 more
wiley   +1 more source

The effects of propionate on blood pressure and arterial function. [PDF]

J Hypertens
Seidel M, Kaess L, Seibert FS, Anft M, Skrzypczyk S, Stervbo U, Kohut E, Ceylan U, Motte J, Gold R, Babel N, Westhoff TH.   +11 more
europepmc   +1 more source

Butyrate Modulates CXCR4 Expression and IL‐5‐Induced Inflammatory Responses in Human Eosinophils

Allergy, EarlyView.
Emiko Matsuyama, Jun Miyata, Yusuke Kawashima, Ryo Konno, Yoshinori Hasegawa, Masahito Mizobe, Yuri Fukasawa, Ryuta Onozato, Yo Otsu, Keeya Sunata, Hisashi Sasaki, Katsunori Masaki, Hiroki Kabata, Makoto Arita, Koichi Fukunaga   +14 more
wiley   +1 more source

Common pathways and outliers in glucose catabolism across Trypanosomatidae

The FEBS Journal, EarlyView.
Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes, Mayke B. Alencar, Ariel M. Silber, Ingrid Škodová‐Sveráková, Kristína Záhonová, Vyacheslav Yurchenko   +5 more
wiley   +1 more source

Plasma short-chain fatty acids are associated with COPD and COPD phenotypes. [PDF]

BMC Pulm Med
Rotevatn AØ, Eagan TM, McCann A, Laupsa-Borge J, Tangedal S, Husebø GR, Nielsen R.   +6 more
europepmc   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

Metabolic and reproductive responses to calcium propionate and 1,25-dihydroxyvitamin D3 in transition dairy cows. [PDF]

Open Vet J
El-Hawary AFA, Gabr AEAE, Mahdy TMM, Mehany AA, Shaarawy ABM, El-Maghraby EFA.   +5 more
europepmc   +1 more source